N-(3-Phthalimido-2-(R)-hydroxypropyl)-3-fluoro-4-(Morpholinyl)aniline

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Names

[ CAS No. ]:
874340-08-6

[ Name ]:
N-(3-Phthalimido-2-(R)-hydroxypropyl)-3-fluoro-4-(Morpholinyl)aniline

[Synonym ]:
2-[(2R)-3-[[3-Fluoro-4-(4-morpholinyl)phenyl]amino]-2-hydroxypropyl]-1H-isoindole-1,3(2H)-dione
N-[3-phthalimido-2-(R)-hydroxypropyl]-3-fluoro-4-(morpholinyl)-aniline
Linezolid Impurity 18

Chemical & Physical Properties

[ Molecular Formula ]:
C21H22FN3O4

[ Molecular Weight ]:
399.41500

[ Exact Mass ]:
399.15900

[ PSA ]:
82.11000

[ LogP ]:
1.80720

[ Storage condition ]:
2-8°C

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • N-[3-chloro-2-(R)-hydroxypropyl]-3-fluoro-4-(morpholin-4-yl)aniline
  • Potassium phthalimide
  • 3-Fluoro-4-morpholinoaniline
  • (S)-N-Glycidylphthalimide

DownStream

  • (R)-N-[[3-[3-Fluoro-4-[4-morpholinyl]phenyl]-2-oxo-5-oxazolidinyl]methyl]phthalimide

Related Compounds

  • benzyl N-{5-oxo-5lambda6-thia-8-azaspiro[3.5]nonan-5-ylidene}carbamate
  • 3-(Dimethylphosphoryl)-5-(2,2,2-trifluoroacetamido)benzoic acid
  • 3'-(2,2,2-Trifluoroacetamido)-[1,1'-biphenyl]-3-carboxylic acid
  • 3-[(2,2,2-Trifluoroacetamido)methyl]thieno[3,2-b]thiophene-2-carboxylic acid
  • 2-[(2,2,2-trifluoroacetamido)methyl]-4H,5H,6H,7H-pyrazolo[1,5-a]pyridine-3-carboxylic acid
  • 4-[(2,2,2-trifluoroacetamido)methyl]-4H,5H,6H,7H-pyrazolo[1,5-a]pyridine-3-carboxylic acid
  • rac-(1R,3R)-2,2-dimethyl-3-(thiophen-3-yl)cyclopropan-1-amine
  • 2-Benzyl-3-(2,2,2-trifluoroacetamido)butanoic acid
  • 2-{[1-(2,2,2-Trifluoroacetyl)-3-(trifluoromethyl)azetidin-3-yl]oxy}acetic acid
  • 5-Bromo-2-{[(tert-butoxy)carbonyl][(furan-2-yl)methyl]amino}pyrimidine-4-carboxylic acid
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