N-(3-Phthalimido-2-(R)-hydroxypropyl)-3-fluoro-4-(Morpholinyl)aniline

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Names

[ CAS No. ]:
874340-08-6

[ Name ]:
N-(3-Phthalimido-2-(R)-hydroxypropyl)-3-fluoro-4-(Morpholinyl)aniline

[Synonym ]:
2-[(2R)-3-[[3-Fluoro-4-(4-morpholinyl)phenyl]amino]-2-hydroxypropyl]-1H-isoindole-1,3(2H)-dione
N-[3-phthalimido-2-(R)-hydroxypropyl]-3-fluoro-4-(morpholinyl)-aniline
Linezolid Impurity 18

Chemical & Physical Properties

[ Molecular Formula ]:
C21H22FN3O4

[ Molecular Weight ]:
399.41500

[ Exact Mass ]:
399.15900

[ PSA ]:
82.11000

[ LogP ]:
1.80720

[ Storage condition ]:
2-8°C

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • N-[3-chloro-2-(R)-hydroxypropyl]-3-fluoro-4-(morpholin-4-yl)aniline
  • Potassium phthalimide
  • 3-Fluoro-4-morpholinoaniline
  • (S)-N-Glycidylphthalimide

DownStream

  • (R)-N-[[3-[3-Fluoro-4-[4-morpholinyl]phenyl]-2-oxo-5-oxazolidinyl]methyl]phthalimide