N-(3-Phthalimido-2-(R)-hydroxypropyl)-3-fluoro-4-(Morpholinyl)aniline

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Names

[ CAS No. ]:
874340-08-6

[ Name ]:
N-(3-Phthalimido-2-(R)-hydroxypropyl)-3-fluoro-4-(Morpholinyl)aniline

[Synonym ]:
2-[(2R)-3-[[3-Fluoro-4-(4-morpholinyl)phenyl]amino]-2-hydroxypropyl]-1H-isoindole-1,3(2H)-dione
N-[3-phthalimido-2-(R)-hydroxypropyl]-3-fluoro-4-(morpholinyl)-aniline
Linezolid Impurity 18

Chemical & Physical Properties

[ Molecular Formula ]:
C21H22FN3O4

[ Molecular Weight ]:
399.41500

[ Exact Mass ]:
399.15900

[ PSA ]:
82.11000

[ LogP ]:
1.80720

[ Storage condition ]:
2-8°C

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • N-[3-chloro-2-(R)-hydroxypropyl]-3-fluoro-4-(morpholin-4-yl)aniline
  • Potassium phthalimide
  • 3-Fluoro-4-morpholinoaniline
  • (S)-N-Glycidylphthalimide

DownStream

  • (R)-N-[[3-[3-Fluoro-4-[4-morpholinyl]phenyl]-2-oxo-5-oxazolidinyl]methyl]phthalimide

Related Compounds

  • (2E)-N-[1-cyano-2-(3,4-difluorophenoxy)-1-methylethyl]-4-(dimethylamino)but-2-enamide
  • rac-(1R,6S)-2-[2-(4-chlorophenyl)ethenesulfonyl]-2-azabicyclo[4.1.0]heptane-1-carboxamide
  • N-(3,4-dihydro-2H-1-benzopyran-4-yl)oxirane-2-carboxamide
  • N-(4,5-dichloropyridin-2-yl)-3-(ethenesulfonyl)propanamide
  • tert-butyl N-({1-[4-(prop-2-enamido)benzoyl]piperidin-3-yl}methyl)carbamate
  • 2-chloro-N-{[1,2,4]triazolo[1,5-a]pyrazin-8-yl}acetamide
  • 2-cyano-3-[4-(1,3-dioxolan-2-yl)phenyl]-N-(propan-2-yl)prop-2-enamide
  • N-[2-(2-oxo-1,3-oxazolidin-3-yl)ethyl]-4-phenyl-1-(prop-2-enoyl)piperidine-4-carboxamide
  • N-[3-(morpholin-4-yl)pyridin-4-yl]-1-(prop-2-enoyl)piperidine-4-carboxamide
  • N-[3-(5-methyl-2,3-dihydro-1H-indol-1-yl)-3-oxopropyl]prop-2-enamide
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