3-[1-(1-hydroxypyridin-2-ylidene)ethylimino]-1,1-dimethyl-thiourea

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Names

[ CAS No. ]:
87587-01-7

[ Name ]:
3-[1-(1-hydroxypyridin-2-ylidene)ethylimino]-1,1-dimethyl-thiourea

[Synonym ]:
4-Methyl-1-(1-(2-pyridyl)ethylidene)-3-thiosemicarbazide
2-acetylpyridine N-oxide N(4)-dimethylthiosemicarbazone
KETONE,METHYL 2-PYRIDYL,4-METHYL-3-THIOSEMICARBAZONE
2-acetylpyridine (4)N-methyl thiosemicarbazone
Hapmtsc
2-Acetylpyridine-4-methyl-3-thiosemicarbazone
Semicarbazide,4-methyl-1-(1-(2-pyridyl)ethylidene)-3-thio
2-Acetylpyridine-N-oxide 4N-dimethylthiosemicarbazone
2-acetylpyridine N(4)-methyl-thiosemicarbazone
2-acetylpyridine 4-methylthiosemicarbazone
2-acetylpyridine-(4)-N-methylthiosemicarbazine

Chemical & Physical Properties

[ Density]:
1.19g/cm3

[ Boiling Point ]:
330ºC at 760 mmHg

[ Molecular Formula ]:
C10H14N4OS

[ Molecular Weight ]:
238.30900

[ Flash Point ]:
153.4ºC

[ Exact Mass ]:
238.08900

[ PSA ]:
85.18000

[ LogP ]:
1.66610

[ Index of Refraction ]:
1.594

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
OB5590000
CHEMICAL NAME :
Ketone, methyl 2-pyridyl, 1-oxide, 4,4-dimethyl-3-thiosemicarbazone
CAS REGISTRY NUMBER :
87587-01-7
LAST UPDATED :
199612
DATA ITEMS CITED :
1
MOLECULAR FORMULA :
C10-H14-N4-O-S
MOLECULAR WEIGHT :
238.34

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE :
Subcutaneous
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
160 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
JMCMAR Journal of Medicinal Chemistry. (American Chemical Soc., Distribution Office Dept. 223, POB POB 57136, West End Stn., Washington, DC 20037) V.6- 1963- Volume(issue)/page/year: 27,87,1984

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • methyl 3-(1-(2-pyridinyl 1-oxide)ethylidene)hydrazinecarbodithioate
  • Dimethylamine
  • 1-(1-oxidopyridin-6-yl)ethanone
  • Hydrazinecarbothioamide, N,N-dimethyl-
  • 2-Acetopyridine

DownStream

Related Compounds

  • 3-(5-Fluoro-2-hydroxyphenyl)pentanedioic acid
  • 1-(Cyclopropylmethyl)-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridin-2-one
  • Riboflavin 5a(2)-(trihydrogen diphosphate), 7-demethyl-7-ethyl-, Pa(2)a5a(2)-ester with adenosine
  • 3-Fluoro-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-5-(trifluoromethyl)pyridine
  • 7-[Tetrahydro-3,5-dihydroxy-6-(3-hydroxy-1-octen-1-yl)-2H-pyran-2-yl]-5-heptenoic acid
  • 1-Naphthalenesulfonic acid, 3,3a(2)-[cyclohexylidenebis(4,1-phenyleneazo)]bis[4-hydroxy-
  • 6-Bromo-4-methylbenzo[d]oxazole
  • 5-cyclopropyl-1-(1-hydroxypropan-2-yl)-1H-1,2,3-triazole-4-carbaldehyde
  • N-{8-azaspiro[4.5]decan-1-yl}butanamide
  • 5-Bromo-3-ethyl-6-(4-fluoro-3-methylphenyl)-3,4-dihydropyrimidin-4-one