5-Thiopyridoxal hydrochloride

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Names

[ CAS No. ]:
876-85-7

[ Name ]:
5-Thiopyridoxal hydrochloride

Chemical & Physical Properties

[ Density]:
1.308g/cm3

[ Boiling Point ]:
469.8ºC at 760 mmHg

[ Molecular Formula ]:
C₈H₁₂ClNO₂S

[ Molecular Weight ]:
221.70400

[ Flash Point ]:
237.9ºC

[ Exact Mass ]:
221.02800

[ PSA ]:
92.15000

[ LogP ]:
1.81970

[ Index of Refraction ]:
1.629

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: UT5005000

CHEMICAL NAME :: 4-Pyridinemethanol, 3-hydroxy-5-(mercaptomethyl)-2-methyl-, hydrochloride

CAS REGISTRY NUMBER :: 876-85-7

LAST UPDATED :: 199309

DATA ITEMS CITED :: 8

MOLECULAR FORMULA :: C8-H9-N-O2-S.Cl-H

MOLECULAR WEIGHT :: 219.70

WISWESSER LINE NOTATION :: T6NJ B1 CQ D1Q E1SH &GH

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 3 gm/kg

TOXIC EFFECTS :: Behavioral - convulsions or effect on seizure threshold Behavioral - excitement

REFERENCE :: ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag, Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951- Volume(issue)/page/year: 11,922,1961

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Subcutaneous

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 430 mg/kg

TOXIC EFFECTS :: Behavioral - convulsions or effect on seizure threshold Behavioral - excitement

REFERENCE :: ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag, Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951- Volume(issue)/page/year: 11,922,1961

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 240 mg/kg

TOXIC EFFECTS :: Behavioral - convulsions or effect on seizure threshold Behavioral - excitement

REFERENCE :: ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag, Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951- Volume(issue)/page/year: 11,922,1961

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 684 mg/kg

TOXIC EFFECTS :: Behavioral - convulsions or effect on seizure threshold Lungs, Thorax, or Respiration - dyspnea

REFERENCE :: ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag, Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951- Volume(issue)/page/year: 11,922,1961

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 350 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: CPBTAL Chemical and Pharmaceutical Bulletin. (Japan Pub. Trading Co., USA, 1255 Howard St., San Francisco, CA 94103) V.6- 1958- Volume(issue)/page/year: 22,409,1974

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Subcutaneous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 440 mg/kg

TOXIC EFFECTS :: Behavioral - convulsions or effect on seizure threshold Lungs, Thorax, or Respiration - dyspnea

REFERENCE :: ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag, Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951- Volume(issue)/page/year: 11,922,1961

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 227 mg/kg

TOXIC EFFECTS :: Behavioral - convulsions or effect on seizure threshold Lungs, Thorax, or Respiration - dyspnea

REFERENCE :: ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag, Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951- Volume(issue)/page/year: 11,922,1961

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Mammal - cat

DOSE/DURATION :: 124 mg/kg

TOXIC EFFECTS :: Behavioral - convulsions or effect on seizure threshold Gastrointestinal - changes in structure or function of salivary glands Gastrointestinal - hypermotility, diarrhea

REFERENCE :: ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag, Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951- Volume(issue)/page/year: 11,922,1961

Related Compounds

W-5 hydrochloride
4-Aminobenzo-15-crown-5 hydrochloride
5-Chlorotryptamine hydrochloride
5-Nitroisoindoline hydrochloride (1:1)
5-Benzyloxytryptamine hydrochloride
5-chloropentanimidamide hydrochloride
1-(5-Hydroxy-2,2-dimethylcyclohexyl)-1,2-dihydropyrimidin-2-one
4-nitro-N-{[1-(piperidin-4-yl)-1H-1,2,3-triazol-4-yl]methyl}benzene-1-sulfonamide
1-(5-Hydroxy-2,2-dimethylcyclohexyl)-1,2-dihydropyrazin-2-one
3-(4,5-dimethyl-1H-imidazol-1-yl)-4,4-dimethylcyclohexan-1-ol
1-(5-Hydroxy-2,2-dimethylcyclohexyl)-3-methylimidazolidin-2-one
4,4-dimethyl-3-[4-(propan-2-yl)-1H-pyrazol-1-yl]cyclohexan-1-ol
6-[Tert-butyl(methyl)amino]spiro[4.5]decan-8-ol
6-[Ethyl(2-methylbutyl)amino]spiro[4.5]decan-8-ol
6-{[3-(Dimethylamino)propyl](methyl)amino}spiro[4.5]decan-8-ol
6-[Cyclopropyl(methyl)amino]spiro[4.5]decan-8-ol

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