mitoflaxone

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Names

[ CAS No. ]:
87626-55-9

[ Name ]:
mitoflaxone

[Synonym ]:
(4-Oxo-2-phenyl-4H-chromen-8-yl)acetic acid
(2-phenyl-4-oxo-4H-1-benzopyran-8-yl)acetic acid
flavone 8-acetic acid
4H-1-Benzopyran-8-acetic acid, 4-oxo-2-phenyl-
mitoflaxone
LM-975
Flavone acetic acid
Mitoflaxona [INN-Spanish]
Mitoflaxonum [INN-Latin]

Chemical & Physical Properties

[ Density]:
1.4±0.1 g/cm3

[ Boiling Point ]:
507.9±50.0 °C at 760 mmHg

[ Molecular Formula ]:
C17H12O4

[ Molecular Weight ]:
280.275

[ Flash Point ]:
192.8±23.6 °C

[ Exact Mass ]:
280.073547

[ PSA ]:
67.51000

[ LogP ]:
2.84

[ Vapour Pressure ]:
0.0±1.4 mmHg at 25°C

[ Index of Refraction ]:
1.649

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
DJ2106000
CHEMICAL NAME :
4H-1-Benzopyran-8-acetic acid, 4-oxo-2-phenyl-
CAS REGISTRY NUMBER :
87626-55-9
LAST UPDATED :
199612
DATA ITEMS CITED :
4
MOLECULAR FORMULA :
C17-H12-O4
MOLECULAR WEIGHT :
280.29

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intravenous
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
350 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
280 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intravenous
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
392 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value

MUTATION DATA

TEST SYSTEM :
Rodent - mouse
DOSE/DURATION :
200 mg/kg
REFERENCE :
CNREA8 Cancer Research. (Public Ledger Building, Suit 816, 6th & Chestnut Sts., Philadelphia, PA 19106) V.1- 1941- Volume(issue)/page/year: 48,1279,1988

Safety Information

[ HS Code ]:
2918300090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • 4-oxo-2-phenyl-4H-1-benzopyran-8-acetonitrile
  • 8-bromomethyl-2-phenyl-4H-1-benzopyran-4-one

DownStream

  • 4H-1-Benzopyran-8-acetic acid, 4-oxo-2-phenyl-, 2-(diethylamino)ethyl ester,hydrochloride
  • 3-dimethylaminopropyl 2-(4-oxo-2-phenyl-chromen-8-yl)acetate
  • 4H-1-Benzopyran-8-aceticacid, 4-oxo-2-phenyl-, 2-hydroxyethyl ester
  • N-(2-diethylaminoethyl)-2-(4-oxo-2-phenyl-chromen-8-yl)acetamide

Customs

[ HS Code ]: 2918300090

[ Summary ]:
2918300090 other carboxylic acids with aldehyde or ketone function but without other oxygen function, their anhydrides, halides, peroxides, peroxyacids and their derivatives。Supervision conditions:None。VAT:17.0%。Tax rebate rate:9.0%。MFN tariff:6.5%。General tariff:30.0%

Related Compounds

  • 4-((Cyclohexylamino)methyl)benzoic acid hydrochloride
  • 1-[(2,4-Dichlorophenyl)methyl]-N-(1,1-dimethylethyl)-2-methyl-1H-indole-3-methanamine
  • 2-Methoxy-6-(pyrazol-1-yl)-benzonitrile
  • 1H-3-Benzazepin-7-ol, 8-chloro-2,3,4,5-tetrahydro-5-(3-iodophenyl)-3-methyl-, (S)-
  • (4-Methyl-tetrahydro-furan-2-yl)-methanol
  • N-(1-cyanocyclopentyl)-2-[4-(4-fluorobenzenesulfonyl)-1,4-diazepan-1-yl]acetamide
  • 4,5,6,7-Tetrahydrobenzo[d]isoxazole-3-carbaldehyde
  • tert-Butyl-DL-alanine
  • tert-butyl N-[(5-bromothiophen-2-yl)methyl]-N-methylcarbamate
  • 4-amino-N-[2-tert-butyl-1-(tetrahydro-2H-pyran-4-ylmethyl)-1H-benzimidazol-5-yl]-N-ethylbenzenesulfonamide