N-propan-2-yl-4-(2-trimethylsilylethynyl)pyrimidin-2-amine

Names

[ CAS No. ]:
876521-30-1

[ Name ]:
N-propan-2-yl-4-(2-trimethylsilylethynyl)pyrimidin-2-amine

[Synonym ]:
2-iso-propylamino-4-[trimethylsilylethynyl]pyrimidine
2-Pyrimidinamine,N-(1-methylethyl)-4-[(trimethylsilyl)ethynyl]

Chemical & Physical Properties

[ Molecular Formula ]:
C12H19N3Si

[ Molecular Weight ]:
233.38500

[ Exact Mass ]:
233.13500

[ PSA ]:
37.81000

[ LogP ]:
2.59880

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • TMS-acetylene
  • isopropylamine
  • 2-Chloro-4-trimethylsilanylethynyl-pyrimidine

DownStream

  • 4-ethynyl-N-propan-2-ylpyrimidin-2-amine
  • 4-[2-(4-fluorophenyl)ethynyl]-N-propan-2-ylpyrimidin-2-amine
  • 1-(4-fluorophenyl)-2-[2-(propan-2-ylamino)pyrimidin-4-yl]ethane-1,2-dione

Related Compounds

  • tert-butyl N-[2-(3,5-dichlorophenyl)-2-hydroxyethyl]carbamate
  • methyl 4-amino-3-(2,3-dihydro-1H-inden-2-yl)butanoate
  • tert-butyl N-(2-cyclohexyl-1-hydroxypropan-2-yl)carbamate
  • {2,2-Dimethyl-1-[(methylsulfanyl)methyl]cyclopropyl}methanamine
  • 2-methyl-1-{1H-pyrrolo[2,3-b]pyridin-3-yl}propan-2-ol
  • 2-[1-(2-Methoxypyridin-4-yl)cyclopropyl]propan-2-amine
  • (2R)-1-[1-(2-methylpropyl)-1H-pyrazol-5-yl]propan-2-amine
  • 4-(Aminomethyl)-4-(3-bromopyridin-2-yl)cyclohexan-1-ol
  • 4-(Aminomethyl)-4-(5-chlorofuran-2-yl)cyclohexan-1-ol
  • (2R)-4-(5-bromofuran-2-yl)butan-2-amine
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