N-propan-2-yl-4-(2-trimethylsilylethynyl)pyrimidin-2-amine

Names

[ CAS No. ]:
876521-30-1

[ Name ]:
N-propan-2-yl-4-(2-trimethylsilylethynyl)pyrimidin-2-amine

[Synonym ]:
2-iso-propylamino-4-[trimethylsilylethynyl]pyrimidine
2-Pyrimidinamine,N-(1-methylethyl)-4-[(trimethylsilyl)ethynyl]

Chemical & Physical Properties

[ Molecular Formula ]:
C12H19N3Si

[ Molecular Weight ]:
233.38500

[ Exact Mass ]:
233.13500

[ PSA ]:
37.81000

[ LogP ]:
2.59880

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • TMS-acetylene
  • isopropylamine
  • 2-Chloro-4-trimethylsilanylethynyl-pyrimidine

DownStream

  • 4-ethynyl-N-propan-2-ylpyrimidin-2-amine
  • 4-[2-(4-fluorophenyl)ethynyl]-N-propan-2-ylpyrimidin-2-amine
  • 1-(4-fluorophenyl)-2-[2-(propan-2-ylamino)pyrimidin-4-yl]ethane-1,2-dione