4-[2-(4-fluorophenyl)ethynyl]-N-propan-2-ylpyrimidin-2-amine

Names

[ CAS No. ]:
876521-35-6

[ Name ]:
4-[2-(4-fluorophenyl)ethynyl]-N-propan-2-ylpyrimidin-2-amine

[Synonym ]:
2-iso-propylamino-4-[(4-fluorophenyl)ethynyl]pyrimidine
2-Pyrimidinamine,4-[(4-fluorophenyl)ethynyl]-N-(1-methylethyl)

Chemical & Physical Properties

[ Molecular Formula ]:
C15H14FN3

[ Molecular Weight ]:
255.29000

[ Exact Mass ]:
255.11700

[ PSA ]:
37.81000

[ LogP ]:
2.90880

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • 4-ethynyl-N-propan-2-ylpyrimidin-2-amine
  • 4-Fluoroiodobenzene
  • N-propan-2-yl-4-(2-trimethylsilylethynyl)pyrimidin-2-amine
  • 2-Chloro-4-trimethylsilanylethynyl-pyrimidine
  • isopropylamine
  • 2-chloro-4-(4-fluoro-phenylethynyl)-pyrimidine

DownStream

  • 1-(4-fluorophenyl)-2-[2-(propan-2-ylamino)pyrimidin-4-yl]ethane-1,2-dione