1H-v-Triazolo(4,5-d)pyrimidine, 7-amino-5-(methylthio)-

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Names

[ CAS No. ]:
87866-19-1

[ Name ]:
1H-v-Triazolo(4,5-d)pyrimidine, 7-amino-5-(methylthio)-

[Synonym ]:
2-Methylthio-6-amino-8-azapurine

Chemical & Physical Properties

[ Density]:
1.67g/cm3

[ Boiling Point ]:
541.2ºC at 760mmHg

[ Molecular Formula ]:
C5H6N6S

[ Molecular Weight ]:
182.20600

[ Flash Point ]:
281.1ºC

[ Exact Mass ]:
182.03700

[ PSA ]:
118.67000

[ LogP ]:
0.63320

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
XZ5740000
CHEMICAL NAME :
1H-v-Triazolo(4,5-d)pyrimidine, 7-amino-5-(methylthio)-
CAS REGISTRY NUMBER :
87866-19-1
LAST UPDATED :
199709
DATA ITEMS CITED :
1
MOLECULAR FORMULA :
C5-H6-N6-S
MOLECULAR WEIGHT :
182.23

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
1250 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
FATOAO Farmakologiya i Toksikologiya (Moscow). For English translation, see PHTXA6 and RPTOAN. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.2- 1939- Volume(issue)/page/year: 46(5),104,1983

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • 4,5,6-Pyrimidinetriamine,2-(methylthio)-

DownStream

Related Compounds

  • 5-Bromo-2-[3-(morpholine-4-carbonyl)piperidin-1-yl]pyridine-3-carbonitrile
  • 1-(5-Tert-butyl-1,3,4-thiadiazol-2-yl)-4-(4,4-difluoropiperidine-1-carbonyl)piperidine
  • 1-(4-{[1-(Oxan-4-yl)piperidin-4-yl]oxy}but-2-yn-1-yl)-4-phenylpiperazine
  • N-{1-[(2-cyclopentyl-1,3-thiazol-4-yl)methyl]piperidin-4-yl}-N-methylpyridin-2-amine
  • N-[(2,3-dihydro-1,4-benzodioxin-6-yl)methyl]-N,5-dimethyl-1,3,4-thiadiazol-2-amine
  • 2-[(1-methyl-1H-imidazol-5-yl)methyl]-6-phenyl-2-azaspiro[3.3]heptane
  • 4-[1-(4-Ethyl-1,3-benzothiazol-2-yl)azetidin-3-yl]piperazin-2-one
  • 1-cyclopentyl-N-(2-fluorophenyl)-1H-1,2,3-triazole-4-carboxamide
  • N-[(2,3-dihydro-1,4-benzodioxin-6-yl)methyl]-N-methylpyrimidin-2-amine
  • N-[(2,3-dihydro-1,4-benzodioxin-6-yl)methyl]-N-methylpyrazin-2-amine