o-nitroaniline

Suppliers

Names

[ CAS No. ]:
88-69-7

[ Name ]:
o-nitroaniline

[Synonym ]:
Phenol, o-isopropyl-
QR BY1&1
1-Hydroxy-2-isopropylbenzene
Phenol, 2-(1-methylethyl)-
EINECS 201-852-8
MFCD00002224
o-Cumenol
o-nitroaniline
2-Isopropylphenol
o-Hydroxycumene
2-(1-Methylethyl)phenol
2-propan-2-ylphenol

Chemical & Physical Properties

[ Density]:
1.0±0.1 g/cm3

[ Boiling Point ]:
213.5±0.0 °C at 760 mmHg

[ Melting Point ]:
12-16 °C(lit.)

[ Molecular Formula ]:
C₉H₁₂O

[ Molecular Weight ]:
136.191

[ Flash Point ]:
88.9±0.0 °C

[ Exact Mass ]:
136.088821

[ PSA ]:
20.23000

[ LogP ]:
2.82

[ Vapour Pressure ]:
0.1±0.4 mmHg at 25°C

[ Index of Refraction ]:
1.526

[ Water Solubility ]:
insoluble

MSDS

Click to get detail MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: SL5900000

CHEMICAL NAME :: Phenol, o-isopropyl-

CAS REGISTRY NUMBER :: 88-69-7

BEILSTEIN REFERENCE NO. :: 1363322

LAST UPDATED :: 199712

DATA ITEMS CITED :: 5

MOLECULAR FORMULA :: C9-H12-O

MOLECULAR WEIGHT :: 136.21

WISWESSER LINE NOTATION :: QR BY1&1

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 100 mg/kg

TOXIC EFFECTS :: Behavioral - sleep

REFERENCE :: JMCMAR Journal of Medicinal Chemistry. (American Chemical Soc., Distribution Office Dept. 223, POB POB 57136, West End Stn., Washington, DC 20037) V.6- 1963- Volume(issue)/page/year: 23,1350,1980 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - 83610 No. of Facilities: 23 (estimated) No. of Industries: 1 No. of Occupations: 1 No. of Employees: 495 (estimated)

Safety Information

[ Symbol ]:

GHS05, GHS07

[ Signal Word ]:
Danger

[ Hazard Statements ]:
H302-H314

[ Precautionary Statements ]:
P280-P305 + P351 + P338-P310

[ Personal Protective Equipment ]:
Faceshields;full-face respirator (US);Gloves;Goggles;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter

[ Hazard Codes ]:
Xn:Harmful;

[ Risk Phrases ]:
R34

[ Safety Phrases ]:
S26-S36/37/39-S45-S28

[ RIDADR ]:
UN 3145 8/PG 2

[ WGK Germany ]:
3

[ RTECS ]:
SL5900000

[ Packaging Group ]:
II

[ Hazard Class ]:
8

[ HS Code ]:
29071900

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

1-Bromo-2-(1-Methylethyl)Benzene
(2-Isopropylphenyl)boronic acid
Benzene,1-methoxy-2-(1-methylethyl)-
propene
Phenol
Isopropoxybenzene
Methylmagnesium chloride
carbonic acid tert-butyl ester 2-formyl-phenyl ester
Isopropanol

DownStream

2-Isopropylphenylisocyanate
4-Isopropoxyacetophenone
4-Hydroxyacetophenone
Isopropyl 2-Isopropylphenyl Ether
2-ISOPROPYL-4-METHYLPHENOL
2-tert-butyl-6-propan-2-ylphenol
6-Isopropyl-7-methoxy-1-tetralone
2,4-DIISOPROPYLPHENOL
Phenol
Propofol

Customs

[ HS Code ]: 2907191010

[ Summary ]:
HS: 2907191010 2-isopropylphenol Tax rebate rate:9.0% Supervision conditions:AB(certificate of inspection for goods inward,certificate of inspection for goods outward) VAT:17.0% MFN tariff:4.0% General tariff:11.0%

Articles

Calculating virtual log P in the alkane/water system (log P(N)(alk)) and its derived parameters deltalog P(N)(oct-alk) and log D(pH)(alk).

J. Med. Chem. 48 , 3269-79, (2005)

Growing interest in the use of both the logarithm of the partition coefficient of the neutral species in the alkane/water system (log P(N)(alk)) and the difference between log P(N)(oct) (the logarithm...

Cellular apoptosis and cytotoxicity of phenolic compounds: a quantitative structure-activity relationship study.

J. Med. Chem. 48 , 7234-42, (2005)

In this comprehensive study on the caspase-mediated apoptosis-inducing effect of 51 substituted phenols in a murine leukemia cell line (L1210), we determined the concentrations needed to induce caspas...

Importance of solvent association in the estimation of antioxidant properties of phenolic compounds by DPPH method.

J. Food Sci. Technol. 52 , 4523-9, (2015)

The presented paper shows the influence of temperature increase in the range typically used during antioxidant measurements (15-35 °C) on the estimation of antioxidant properties of phenolic compounds...