2-Nitroaniline
Suppliers
Names
[ CAS No. ]:
88-74-4
[ Name ]:
2-Nitroaniline
[Synonym ]:
1-amino-2-nitro-benzene
Nitroaniline
Devol Orange B
EINECS 201-855-4
Benzenamine, 2-nitro-
Azoic Diazo Component 6
aniline, 2-nitro-
MFCD00007687
aniline, nitro-
o-Nitraniline
1-nitro-2-aminobenzene
2-nitrophenylamine
2-Aminonitrobenzene
1-Amino-2-nitrobenzene
Benzenamine,2-nitro
ortho-nitro-aniline
2-Nitrobenzenamine
o-nitroaniline
2-nitro-aniline
Chemical & Physical Properties
[ Density]:
1.3±0.1 g/cm3
[ Boiling Point ]:
284.9±13.0 °C at 760 mmHg
[ Melting Point ]:
70-73 °C(lit.)
[ Molecular Formula ]:
C6H6N2O2
[ Molecular Weight ]:
138.124
[ Flash Point ]:
126.1±19.8 °C
[ Exact Mass ]:
138.042923
[ PSA ]:
71.84000
[ LogP ]:
1.83
[ Vapour Pressure ]:
0.0±0.6 mmHg at 25°C
[ Index of Refraction ]:
1.634
[ Water Solubility ]:
1.1 g/L (20 ºC)
MSDS
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- BY6650000
- CHEMICAL NAME :
- Aniline, o-nitro-
- CAS REGISTRY NUMBER :
- 88-74-4
- LAST UPDATED :
- 199710
- DATA ITEMS CITED :
- 20
- MOLECULAR FORMULA :
- C6-H6-N2-O2
- MOLECULAR WEIGHT :
- 138.14
- WISWESSER LINE NOTATION :
- ZR BNW
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 1600 mg/kg
- TOXIC EFFECTS :
- Behavioral - somnolence (general depressed activity) Behavioral - convulsions or effect on seizure threshold
- TYPE OF TEST :
- LDLo - Lowest published lethal dose
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 800 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 1070 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - guinea pig
- DOSE/DURATION :
- 2350 mg/kg
- TOXIC EFFECTS :
- Behavioral - somnolence (general depressed activity) Behavioral - convulsions or effect on seizure threshold
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Bird - quail
- DOSE/DURATION :
- 750 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Unreported
- SPECIES OBSERVED :
- Mammal - species unspecified
- DOSE/DURATION :
- 9441 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Bird - wild bird species
- DOSE/DURATION :
- 750 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- Micronucleus test
MUTATION DATA
- TYPE OF TEST :
- Cytogenetic analysis
- TEST SYSTEM :
- Rodent - hamster Ovary
- DOSE/DURATION :
- 10 mmol/L
- REFERENCE :
- MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 320,273,1994 *** OCCUPATIONAL EXPOSURE LIMITS *** OEL-RUSSIA:STEL 0.5 mg/m3;Skin JAN 1993 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - 84091 No. of Facilities: 28 (estimated) No. of Industries: 1 No. of Occupations: 2 No. of Employees: 336 (estimated) NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - 84091 No. of Facilities: 54 (estimated) No. of Industries: 2 No. of Occupations: 3 No. of Employees: 1612 (estimated) No. of Female Employees: 455 (estimated)
Safety Information
[ Symbol ]:
GHS06, GHS08
[ Signal Word ]:
Danger
[ Hazard Statements ]:
H301-H311-H331-H373-H412
[ Precautionary Statements ]:
P261-P273-P280-P301 + P310-P311
[ Personal Protective Equipment ]:
Eyeshields;Faceshields;Gloves;type P2 (EN 143) respirator cartridges
[ Hazard Codes ]:
T:Toxic
[ Risk Phrases ]:
R23/24/25;R33;R52/53
[ Safety Phrases ]:
S28-S36/37-S45-S61-S28A-S16-S7
[ RIDADR ]:
UN 1661 6.1/PG 2
[ WGK Germany ]:
2
[ RTECS ]:
BY6650000
[ Packaging Group ]:
II
[ Hazard Class ]:
6.1
[ HS Code ]:
2921420090
Synthetic Route
Precursor & DownStream
Precursor
DownStream
Customs
[ HS Code ]: 2921420090
[ Summary ]:
HS:2921420090 aniline derivatives and their salts VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:30.0%
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