BOC-TRANS-4-TOSYLOXY-L-PROLINE METHYL ESTER

Suppliers

Names

[ CAS No. ]:
88043-21-4

[ Name ]:
BOC-TRANS-4-TOSYLOXY-L-PROLINE METHYL ESTER

[Synonym ]:
1-O-tert-butyl 2-O-methyl (2S,4R)-4-(4-methylphenyl)sulfonyloxypyrrolidine-1,2-dicarboxylate
2-Methyl 1-(2-methyl-2-propanyl) (2S,4R)-4-{[(4-methylphenyl)sulfonyl]oxy}-1,2-pyrrolidinedicarboxylate
1,2-Pyrrolidinedicarboxylic acid, 4-[[(4-methylphenyl)sulfonyl]oxy]-, 1-(1,1-dimethylethyl) 2-methyl ester, (2S,4R)-

Chemical & Physical Properties

[ Density]:
1.3±0.1 g/cm3

[ Boiling Point ]:
508.1±50.0 °C at 760 mmHg

[ Melting Point ]:
77.0 to 81.0 °C

[ Molecular Formula ]:
C18H25NO7S

[ Molecular Weight ]:
399.459

[ Flash Point ]:
261.1±30.1 °C

[ Exact Mass ]:
399.135162

[ PSA ]:
107.59000

[ LogP ]:
1.77

[ Vapour Pressure ]:
0.0±1.3 mmHg at 25°C

[ Index of Refraction ]:
1.554

[ Storage condition ]:
2-8°C

MSDS

Click to get detail MSDS

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H319

[ Precautionary Statements ]:
P305 + P351 + P338

[ Hazard Codes ]:
Xi

[ Risk Phrases ]:
36

[ Safety Phrases ]:
26

[ RIDADR ]:
NONH for all modes of transport

[ HS Code ]:
2933990090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • Boc-Hyp-OMe
  • Tosyl chloride
  • H-Hyp-OMe hydrochloride
  • Di-tert-butyl dicarbonate
  • L-Hydroxyproline

DownStream

  • n-boc-cis-4-cyano-l-proline methyl ester
  • Boc-trans-4-cyano-L-proline methyl ester
  • (2S,4S)-1-tert-Butyl 2-methyl 4-aminopyrrolidine-1,2-dicarboxylate
  • N-t-BOC-trans-4-Fluoro-L-proline methyl ester

Customs

[ HS Code ]: 2933990090

[ Summary ]:
2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Articles

Use of cis-[18F]fluoro-proline for assessment of exercise-related collagen synthesis in musculoskeletal connective tissue.

PLoS ONE 6 , e16678, (2011)

Protein turnover in collagen rich tissue is influenced by exercise, but can only with difficulty be studied in vivo due to use of invasive procedure. The present study was done to investigate the poss...


More Articles

Related Compounds

  • Boc-trans-4-cyano-L-proline methyl ester
  • N-BOC-TRANS-4-IODO-L-PROLINE METHYL ESTER
  • N-Boc-trans-4-amino-L-proline methyl ester
  • N-Boc-trans-4-amino-L-proline methyl ester hydrochloride
  • N-t-BOC-trans-4-Fluoro-L-proline methyl ester
  • N-t-BOC-trans-4-Fluoro-L-proline methyl ester