Fmoc-L-hydroxyproline

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Names

[ CAS No. ]:
88050-17-3

[ Name ]:
Fmoc-L-hydroxyproline

[Synonym ]:
1,2-Pyrrolidinedicarboxylic acid, 4-hydroxy-, 1-(9H-fluoren-9-ylmethyl) ester, (2S,4R)-
(2S,4R)-1-(9H-fluoren-9-ylmethoxycarbonyl)-4-hydroxypyrrolidine-2-carboxylic acid
(4R)-1-[(9H-Fluoren-9-ylmethoxy)carbonyl]-4-hydroxy-L-proline
MFCD00151929
Fmoc-Hyp-OH
Fmoc-L-4-hydroxyproline
Fmoc-L-hydroxyproline

Chemical & Physical Properties

[ Density]:
1.4±0.1 g/cm3

[ Boiling Point ]:
595.5±50.0 °C at 760 mmHg

[ Melting Point ]:
189-193ºC

[ Molecular Formula ]:
C20H19NO5

[ Molecular Weight ]:
353.37

[ Flash Point ]:
314.0±30.1 °C

[ Exact Mass ]:
353.126312

[ PSA ]:
87.07000

[ LogP ]:
1.73

[ Vapour Pressure ]:
0.0±1.8 mmHg at 25°C

[ Index of Refraction ]:
1.658

[ Storage condition ]:
2-8°C

MSDS

Click to get detail MSDS

Safety Information

[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ Hazard Codes ]:
Xi

[ Safety Phrases ]:
22-24/25

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

[ HS Code ]:
2933990090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • 9-Fluorenylmethyl chloroformate
  • L-Hydroxyproline
  • Fmoc-Osu
  • trimethylsilyl (2S,4R)-4-(trimethylsilyoxy)pyrrolidine-2-carboxylate

DownStream

  • N-Fmoc-trans-4-hydroxy-L-proline methyl ester
  • (2S,4S)-4-FLUOROPYRROLIDINE-2-CARBOXAMIDE

Customs

[ HS Code ]: 2933990090

[ Summary ]:
2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Related Compounds

  • Fmoc-L-2,5,7-tri-tert-butyl-tryptophan
  • Fmoc-L-Cycpentala-OH
  • Fmoc-L-Ala-OBt
  • FMoc-L-3-Thienylalanine
  • FMOC-L-INDOLINE-2-CARBOXYLIC ACID
  • Fmoc-L-homocystine
  • Ethyl 2-hydrazinyl-4-thiophen-2-ylpyrimidine-5-carboxylate
  • 4-Ethyl-2-(methylthio)pyrimidine-5-carboxylic acid
  • (3S)-3-(3-fluorophenoxy)pyrrolidine
  • Ethyl 4-chloro-2-(3'-nitrophenyl)pyrimidine-5-carboxylate
  • Ethyl 4-hydroxy-2-(3',4'-dichlorobenzyl)pyrimidine-5-carboxylate
  • Ethyl 2-chloro-4-benzylpyrimidine-5-carboxylate
  • 3,4-Dihydro-2,2,6-trimethyl-2H-1-benzopyran-4-methanamine
  • 4-Chloro-2-methyl-1-(methylsulfonyl)benzene
  • 6-(2-Methoxy-4-methylphenoxy)pyridin-3-amine
  • 2-Acetylamino-5-nitro-4-trifluoromethyl-benzoic acid
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