Tetrahydro-1H-pyrrolizine-7a(5H)-acetic acid ethyl ester

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Names

[ CAS No. ]:
88069-56-1

[ Name ]:
Tetrahydro-1H-pyrrolizine-7a(5H)-acetic acid ethyl ester

[Synonym ]:
7a-ethoxycarbonylmethylhexahydro-1H-pyrrolizine
2-pyrrolizidin-8-ylacetic acid ethyl ester

Chemical & Physical Properties

[ Molecular Formula ]:
C11H19NO2

[ Molecular Weight ]:
197.27400

[ Exact Mass ]:
197.14200

[ PSA ]:
29.54000

[ LogP ]:
1.50590

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • Potassium monoethyl malonate
  • Methanol
  • 1,7-Dichloro-4-heptanone

DownStream

  • pilsicainide
  • N-(2-aminophenyl)-2-(1,2,3,5,6,7-hexahydropyrrolizin-8-yl)acetamide
  • N-(2,6-diethylphenyl)-2-(1,2,3,5,6,7-hexahydropyrrolizin-8-yl)acetamide
  • 2-(1,2,3,5,6,7-hexahydropyrrolizin-8-yl)-N-(2-methylphenyl)acetamide
  • 2-(1,2,3,5,6,7-hexahydropyrrolizin-8-yl)-N-(4-methylphenyl)acetamide
  • N-(2-chlorophenyl)-2-(1,2,3,5,6,7-hexahydropyrrolizin-8-yl)acetamide
  • N-(2-bromophenyl)-2-(1,2,3,5,6,7-hexahydropyrrolizin-8-yl)acetamide
  • 2-(1,2,3,5,6,7-hexahydropyrrolizin-8-yl)-N-(2-methoxyphenyl)acetamide
  • 2-(1,2,3,5,6,7-hexahydropyrrolizin-8-yl)-N-(3-methoxyphenyl)acetamide
  • 2-(1,2,3,5,6,7-hexahydropyrrolizin-8-yl)-N-(4-methoxyphenyl)acetamide

Related Compounds

  • 1-Cyclopropyl-2-(4-((4-ethoxyphenyl)sulfonyl)piperazin-1-yl)ethanol
  • 1-Cyclopropyl-2-(4-((5-fluoro-2-methoxyphenyl)sulfonyl)piperazin-1-yl)ethanol
  • 1-Cyclopropyl-2-(4-((2-fluorophenyl)sulfonyl)piperazin-1-yl)ethanol
  • 1-Cyclopropyl-2-(4-((3-methoxyphenyl)sulfonyl)piperazin-1-yl)ethanol
  • tert-Butyl 3-((2-fluorophenyl)methylsulfonamido)piperidine-1-carboxylate
  • tert-Butyl 3-((2-chloropyrimidin-4-yl)oxy)piperidine-1-carboxylate
  • (3-(3-Benzyl-1,2,4-oxadiazol-5-yl)azetidin-1-yl)(4-(trifluoromethoxy)phenyl)methanone
  • tert-Butyl 3-((3-chloro-5-(trifluoromethyl)pyridin-2-yl)oxy)piperidine-1-carboxylate
  • tert-Butyl 3-(thiazol-2-yloxy)piperidine-1-carboxylate
  • tert-Butyl 3-((5-nitro-1H-benzo[d]imidazol-2-yl)oxy)piperidine-1-carboxylate
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