Tetrahydro-1H-pyrrolizine-7a(5H)-acetic acid ethyl ester

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Names

[ CAS No. ]:
88069-56-1

[ Name ]:
Tetrahydro-1H-pyrrolizine-7a(5H)-acetic acid ethyl ester

[Synonym ]:
7a-ethoxycarbonylmethylhexahydro-1H-pyrrolizine
2-pyrrolizidin-8-ylacetic acid ethyl ester

Chemical & Physical Properties

[ Molecular Formula ]:
C11H19NO2

[ Molecular Weight ]:
197.27400

[ Exact Mass ]:
197.14200

[ PSA ]:
29.54000

[ LogP ]:
1.50590

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • Potassium monoethyl malonate
  • Methanol
  • 1,7-Dichloro-4-heptanone

DownStream

  • pilsicainide
  • N-(2-aminophenyl)-2-(1,2,3,5,6,7-hexahydropyrrolizin-8-yl)acetamide
  • N-(2,6-diethylphenyl)-2-(1,2,3,5,6,7-hexahydropyrrolizin-8-yl)acetamide
  • 2-(1,2,3,5,6,7-hexahydropyrrolizin-8-yl)-N-(2-methylphenyl)acetamide
  • 2-(1,2,3,5,6,7-hexahydropyrrolizin-8-yl)-N-(4-methylphenyl)acetamide
  • N-(2-chlorophenyl)-2-(1,2,3,5,6,7-hexahydropyrrolizin-8-yl)acetamide
  • N-(2-bromophenyl)-2-(1,2,3,5,6,7-hexahydropyrrolizin-8-yl)acetamide
  • 2-(1,2,3,5,6,7-hexahydropyrrolizin-8-yl)-N-(2-methoxyphenyl)acetamide
  • 2-(1,2,3,5,6,7-hexahydropyrrolizin-8-yl)-N-(3-methoxyphenyl)acetamide
  • 2-(1,2,3,5,6,7-hexahydropyrrolizin-8-yl)-N-(4-methoxyphenyl)acetamide

Related Compounds

  • 2-[2,5-dioxo-4-(2-thienyl)-3,4,5,7-tetrahydrofuro[3,4-d]pyrimidin-1(2H)-yl]-N-propylacetamide
  • 1-{[5-(pentan-3-yl)-1,2,4-oxadiazol-3-yl]methyl}-4-phenyl-1H,2H,3H,4H,5H,7H-furo[3,4-d]pyrimidine-2,5-dione
  • 1-{[5-(cyclohexylmethyl)-1,2,4-oxadiazol-3-yl]methyl}-4-phenyl-1H,2H,3H,4H,5H,7H-furo[3,4-d]pyrimidine-2,5-dione
  • 1-(2-methoxyethyl)-4-phenyl-4,7-dihydrofuro[3,4-d]pyrimidine-2,5(1H,3H)-dione
  • 1-(2-ethoxyethyl)-4-phenyl-4,7-dihydrofuro[3,4-d]pyrimidine-2,5(1H,3H)-dione
  • 1-(cyclopropylmethyl)-4-phenyl-4,7-dihydrofuro[3,4-d]pyrimidine-2,5(1H,3H)-dione
  • 4-Chloro-5-methoxyindole-3-acetic acid
  • 1-(2-methoxyethyl)-4-(2-thienyl)-4,7-dihydrofuro[3,4-d]pyrimidine-2,5(1H,3H)-dione
  • 1-butyl-4-(2-thienyl)-4,7-dihydrofuro[3,4-d]pyrimidine-2,5(1H,3H)-dione
  • (S)-5-(1-Hydroxyethyl)-1H-pyrazole-3-carboxylic acid
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