Tetrahydro-1H-pyrrolizine-7a(5H)-acetic acid ethyl ester

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Names

[ CAS No. ]:
88069-56-1

[ Name ]:
Tetrahydro-1H-pyrrolizine-7a(5H)-acetic acid ethyl ester

[Synonym ]:
7a-ethoxycarbonylmethylhexahydro-1H-pyrrolizine
2-pyrrolizidin-8-ylacetic acid ethyl ester

Chemical & Physical Properties

[ Molecular Formula ]:
C11H19NO2

[ Molecular Weight ]:
197.27400

[ Exact Mass ]:
197.14200

[ PSA ]:
29.54000

[ LogP ]:
1.50590

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • Potassium monoethyl malonate
  • Methanol
  • 1,7-Dichloro-4-heptanone

DownStream

  • pilsicainide
  • N-(2-aminophenyl)-2-(1,2,3,5,6,7-hexahydropyrrolizin-8-yl)acetamide
  • N-(2,6-diethylphenyl)-2-(1,2,3,5,6,7-hexahydropyrrolizin-8-yl)acetamide
  • 2-(1,2,3,5,6,7-hexahydropyrrolizin-8-yl)-N-(2-methylphenyl)acetamide
  • 2-(1,2,3,5,6,7-hexahydropyrrolizin-8-yl)-N-(4-methylphenyl)acetamide
  • N-(2-chlorophenyl)-2-(1,2,3,5,6,7-hexahydropyrrolizin-8-yl)acetamide
  • N-(2-bromophenyl)-2-(1,2,3,5,6,7-hexahydropyrrolizin-8-yl)acetamide
  • 2-(1,2,3,5,6,7-hexahydropyrrolizin-8-yl)-N-(2-methoxyphenyl)acetamide
  • 2-(1,2,3,5,6,7-hexahydropyrrolizin-8-yl)-N-(3-methoxyphenyl)acetamide
  • 2-(1,2,3,5,6,7-hexahydropyrrolizin-8-yl)-N-(4-methoxyphenyl)acetamide

Related Compounds

  • 4-Chloro-2-(2-pyrimidinyl)benzoic acid
  • 1-(3-Pyridazinyl)-1H-pyrazole-5-carboxylic acid
  • 7-Bromo-1,2,2,4-tetramethyl-1,2-dihydroquinoline
  • 1-(3-Bromopyridin-2-yl)-2,2,2-trifluoroethan-1-ol
  • Methyl 4-amino-3-(difluoromethoxy)-5-iodobenzoate
  • 5-nitro-1H-indole-3-amine
  • 2-Chloro-4-[(piperazin-1-yl)methyl]phenol dihydrochloride
  • 6-Fluoro-3-methylpyrazin-2-amine
  • {[2-(3,4-Dichlorophenoxy)phenyl]methyl}(methyl)amine hydrochloride
  • 3-{1H-pyrrolo[2,3-b]pyridin-3-yl}piperidine dihydrochloride
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