Tetrahydro-1H-pyrrolizine-7a(5H)-acetic acid ethyl ester

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Names

[ CAS No. ]:
88069-56-1

[ Name ]:
Tetrahydro-1H-pyrrolizine-7a(5H)-acetic acid ethyl ester

[Synonym ]:
7a-ethoxycarbonylmethylhexahydro-1H-pyrrolizine
2-pyrrolizidin-8-ylacetic acid ethyl ester

Chemical & Physical Properties

[ Molecular Formula ]:
C11H19NO2

[ Molecular Weight ]:
197.27400

[ Exact Mass ]:
197.14200

[ PSA ]:
29.54000

[ LogP ]:
1.50590

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • Potassium monoethyl malonate
  • Methanol
  • 1,7-Dichloro-4-heptanone

DownStream

  • pilsicainide
  • N-(2-aminophenyl)-2-(1,2,3,5,6,7-hexahydropyrrolizin-8-yl)acetamide
  • N-(2,6-diethylphenyl)-2-(1,2,3,5,6,7-hexahydropyrrolizin-8-yl)acetamide
  • 2-(1,2,3,5,6,7-hexahydropyrrolizin-8-yl)-N-(2-methylphenyl)acetamide
  • 2-(1,2,3,5,6,7-hexahydropyrrolizin-8-yl)-N-(4-methylphenyl)acetamide
  • N-(2-chlorophenyl)-2-(1,2,3,5,6,7-hexahydropyrrolizin-8-yl)acetamide
  • N-(2-bromophenyl)-2-(1,2,3,5,6,7-hexahydropyrrolizin-8-yl)acetamide
  • 2-(1,2,3,5,6,7-hexahydropyrrolizin-8-yl)-N-(2-methoxyphenyl)acetamide
  • 2-(1,2,3,5,6,7-hexahydropyrrolizin-8-yl)-N-(3-methoxyphenyl)acetamide
  • 2-(1,2,3,5,6,7-hexahydropyrrolizin-8-yl)-N-(4-methoxyphenyl)acetamide

Related Compounds

  • 1,3-Bis(methyleneamino)-2-propanol
  • 3-(1H-Benzo[d][1,2,3]triazol-1-yl)-N'-(3-ethoxy-4-hydroxybenzylidene)propanehydrazide
  • 6-methyl-3-[({1-[3-(trifluoromethyl)phenyl]-1H-tetrazol-5-yl}methyl)sulfanyl]-1,2,4-triazin-5-ol
  • 6-[(4-methoxy-7,7-dimethyl-7,8-dihydro-6H-pyrimido[4,5-b][1,4]benzothiazin-9-yl)amino]hexanoic acid
  • 3-(3-(4-(trifluoromethyl)phenyl)-1,2,4-oxadiazol-5-yl)quinolin-4(1H)-one
  • 3-(3-(4-bromophenyl)-1,2,4-oxadiazol-5-yl)quinolin-4(1H)-one
  • 3-(3-(3-bromophenyl)-1,2,4-oxadiazol-5-yl)-6-fluoroquinolin-4(1H)-one
  • 3-(3-(3,4-dimethoxyphenyl)-1,2,4-oxadiazol-5-yl)-6-fluoroquinolin-4(1H)-one
  • 3-(3-(benzo[d][1,3]dioxol-5-yl)-1,2,4-oxadiazol-5-yl)-6-fluoroquinolin-4(1H)-one
  • 3-(3-(pyridin-3-yl)-1,2,4-oxadiazol-5-yl)quinolin-4(1H)-one
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