HELSS

Suppliers

Names

[ CAS No. ]:
88070-98-8

[ Name ]:
HELSS

[Synonym ]:
Haloenol lactone suicide substrate
MFCD00270871
bromoenol lactone
2H-Pyran-2-one, 6-(bromomethylene)tetrahydro-3-(1-naphthalenyl)-, (6Z)-
6-Btnpo
L66J B- FT6VOYTJ CU1E
HELSS
BEL
(6Z)-6-(Bromomethylene)-3-(1-naphthyl)tetrahydro-2H-pyran-2-one
BTNP

Chemical & Physical Properties

[ Density]:
1.5±0.1 g/cm3

[ Boiling Point ]:
467.0±45.0 °C at 760 mmHg

[ Molecular Formula ]:
C16H13BrO2

[ Molecular Weight ]:
317.177

[ Flash Point ]:
236.2±28.7 °C

[ Exact Mass ]:
316.009888

[ PSA ]:
26.30000

[ LogP ]:
4.36

[ Vapour Pressure ]:
0.0±1.2 mmHg at 25°C

[ Index of Refraction ]:
1.716

[ Storage condition ]:
-20°C

MSDS

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H315-H319-H335

[ Precautionary Statements ]:
P261-P305 + P351 + P338

[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves

[ Hazard Codes ]:
Xi: Irritant;

[ Risk Phrases ]:
36/37/38

[ Safety Phrases ]:
26

[ RIDADR ]:
NONH for all modes of transport

Articles

Persistent Nociception Triggered by Nerve Growth Factor (NGF) Is Mediated by TRPV1 and Oxidative Mechanisms.

J. Neurosci. 35 , 8593-603, (2015)

Nerve growth factor (NGF) is elevated in certain chronic pain conditions and is a sufficient stimulus to cause lasting pain in humans, but the actual mechanisms underlying the persistent effects of NG...

Bromoenol Lactone Attenuates Nicotine-Induced Breast Cancer Cell Proliferation and Migration.

PLoS ONE 10 , e0143277, (2015)

Calcium independent group VIA phospholipase A2 (iPLA2β) and Matrix Metalloproteinase-9 (MMP-9) are upregulated in many disease states; their involvement with cancer cell migration has been a recent su...

Cytosolic phospholipase A2 plays a crucial role in ROS/NO signaling during microglial activation through the lipoxygenase pathway.

J. Neuroinflammation 12 , 199, (2015)

Oxidative stress and inflammation are important factors contributing to the pathophysiology of numerous neurological disorders, including Alzheimer's disease, Parkinson's disease, acute stroke, and in...


More Articles


Related Compounds

  • rel-(1R,2R)-2-(Pyridin-2-yl)cyclopropanecarboxylic acid hydrochloride
  • (1S,6R)-2-Azabicyclo[4.2.0]octane;hydrochloride
  • (4R,5S)-1,2-Oxazinane-4,5-diol hydrochloride
  • [(1S,3R)-2,2-Dimethyl-3-[(2-methylpropan-2-yl)oxy]cyclobutyl]methanamine;hydrochloride
  • (1R,2R)-4-Chloro-2-methyl-2,3-dihydro-1H-inden-1-amine;hydrochloride
  • rac-methyl (1R,2S)-2-(piperidin-4-yl)cyclopropane-1-carboxylate
  • Rel-methyl 2-((3R,4S)-4-hydroxypyrrolidin-3-yl)acetate hydrochloride
  • Methyl (3S,4S)-4-[[(2-methylpropan-2-yl)oxycarbonylamino]methyl]pyrrolidine-3-carboxylate;hydrochloride
  • 3-((1H-Imidazol-1-yl)methyl)cyclobutan-1-amine dihydrochloride
  • Methyl 3-(3-aminocyclobutyl)propanoate hydrochloride
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