HELSS

Suppliers

Names

[ Name ]:
HELSS

[Synonym ]:
Haloenol lactone suicide substrate
MFCD00270871
bromoenol lactone
2H-Pyran-2-one, 6-(bromomethylene)tetrahydro-3-(1-naphthalenyl)-, (6Z)-
6-Btnpo
L66J B- FT6VOYTJ CU1E
HELSS
BEL
(6Z)-6-(Bromomethylene)-3-(1-naphthyl)tetrahydro-2H-pyran-2-one
BTNP

Chemical & Physical Properties

[ Density]:
1.5±0.1 g/cm3

[ Boiling Point ]:
467.0±45.0 °C at 760 mmHg

[ Molecular Formula ]:
C₁₆H₁₃BrO₂

[ Molecular Weight ]:
317.177

[ Flash Point ]:
236.2±28.7 °C

[ Exact Mass ]:
316.009888

[ PSA ]:
26.30000

[ LogP ]:
4.36

[ Vapour Pressure ]:
0.0±1.2 mmHg at 25°C

[ Index of Refraction ]:
1.716

[ Storage condition ]:
-20°C

MSDS

Click to get detail MSDS

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H315-H319-H335

[ Precautionary Statements ]:
P261-P305 + P351 + P338

[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves

[ Hazard Codes ]:
Xi: Irritant;

[ Risk Phrases ]:
36/37/38

[ Safety Phrases ]:
26

[ RIDADR ]:
NONH for all modes of transport

Articles

Persistent Nociception Triggered by Nerve Growth Factor (NGF) Is Mediated by TRPV1 and Oxidative Mechanisms.

J. Neurosci. 35 , 8593-603, (2015)

Nerve growth factor (NGF) is elevated in certain chronic pain conditions and is a sufficient stimulus to cause lasting pain in humans, but the actual mechanisms underlying the persistent effects of NG...

Bromoenol Lactone Attenuates Nicotine-Induced Breast Cancer Cell Proliferation and Migration.

PLoS ONE 10 , e0143277, (2015)

Calcium independent group VIA phospholipase A2 (iPLA2β) and Matrix Metalloproteinase-9 (MMP-9) are upregulated in many disease states; their involvement with cancer cell migration has been a recent su...

Cytosolic phospholipase A2 plays a crucial role in ROS/NO signaling during microglial activation through the lipoxygenase pathway.

J. Neuroinflammation 12 , 199, (2015)

Oxidative stress and inflammation are important factors contributing to the pathophysiology of numerous neurological disorders, including Alzheimer's disease, Parkinson's disease, acute stroke, and in...

5-(1-Methoxypropan-2-yl)-4,5,6,7-tetrahydrothieno[3,2-c]pyridine
5-Chloro-6-(3-oxopiperazin-1-yl)nicotinonitrile
4-(4-Methylpyrimidin-2-yl)piperazin-2-one
1-[1-(Furan-2-yl)propan-2-yl]piperidine-4-carbonitrile
1-(6-Ethylpyrimidin-4-yl)piperidine-4-carbonitrile
Azetidin-3-yl(4-(hydroxymethyl)-4-methylpiperidin-1-yl)methanone
(4-(Hydroxymethyl)-4-methylpiperidin-1-yl)(piperidin-2-yl)methanone
(4-(Hydroxymethyl)-4-methylpiperidin-1-yl)(piperidin-3-yl)methanone
(4-(Hydroxymethyl)-4-methylpiperidin-1-yl)(piperidin-4-yl)methanone
(Z)-N'-hydroxy-2-(4-(hydroxymethyl)-4-methylpiperidin-1-yl)acetimidamide

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