Donepezil Hydrochloride

Names

[ CAS No. ]:
884740-09-4

[ Name ]:
Donepezil Hydrochloride

[Synonym ]:
2-[(1-benzylpiperidin-4-yl)methyl]-5,6-dimethoxy-2,3-dihydroinden-1-one,hydrate,hydrochloride

Chemical & Physical Properties

[ Molecular Formula ]:
C₂₄H₃₂ClNO₄

[ Molecular Weight ]:
433.96800

[ Exact Mass ]:
433.20200

[ PSA ]:
48.00000

[ LogP ]:
5.03670

MSDS

Safety Information

[ RIDADR ]:
NONH for all modes of transport

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Articles

Pretreatment with 5-hydroxymethyl-2-furaldehyde blocks scopolamine-induced learning deficit in contextual and spatial memory in male mice.

Pharmacol. Biochem. Behav. 134 , 57-64, (2015)

5-Hydroxymethyl-2-furaldehyde (5-HMF) is a compound derived from the dehydration of certain sugars. The aim of the present study was to evaluate the effect of 5-HMF on the cognitive impairment induced...

Flow-through enzyme immobilized amperometric detector for the rapid screening of acetylcholinesterase inhibitors by flow injection analysis.

J. Pharm. Biomed. Anal. 102 , 267-75, (2015)

A commercially available thin-layer flow-through amperometric detector, with the sensing block customized in an original design, was applied to the screening of drug compounds known as acetylcholinest...

Subchronic treatment of donepezil rescues impaired social, hyperactive, and stereotypic behavior in valproic acid-induced animal model of autism.

PLoS ONE 9(8) , e104927, (2014)

Autism spectrum disorder (ASD) is a group of pervasive developmental disorders with core symptoms such as sociability deficit, language impairment, and repetitive/restricted behaviors. Although worldw...