Fosinopril sodium

Suppliers

Names

[ Name ]:
Fosinopril sodium

[Synonym ]:
Tensozide
Dynacil
Fosinopril sodium
(4S)-4-Cyclohexyl-1-{[(R)-[(1R)-2-methyl-1-(propionyloxy)propoxy](4-phenylbutyl)phosphoryl]acetyl}-L-proline
Fosinorm
Staril
sodium,(2S,4S)-4-cyclohexyl-1-[2-[(2-methyl-1-propanoyloxypropoxy)-(4-phenylbutyl)phosphoryl]acetyl]pyrrolidine-2-carboxylate
(4S)-4-cyclohexyl-1-{[(R)-{[(1R)-2-methyl-1-(propanoyloxy)propyl]oxy}(4-phenylbutyl)phosphoryl]acetyl}-L-proline
MFCD00897699
L-Proline, 4-cyclohexyl-1-[2-[(R)-[(1R)-2-methyl-1-(1-oxopropoxy)propoxy][(1R)-4-phenylbutyl]phosphinyl]acetyl]-, (4S)-
Fositen
L-proline, 4-cyclohexyl-1-[2-[(R)-[[(1R)-2-methyl-1-(1-oxopropoxy)propyl]oxy][(1R)-4-phenylbutyl]phosphinyl]acetyl]-, (4S)-
Fozitec
Elidur

Chemical & Physical Properties

[ Density]:
1.2±0.1 g/cm3

[ Boiling Point ]:
705.7±70.0 °C at 760 mmHg

[ Melting Point ]:
196-198ºC

[ Molecular Formula ]:
C₃₀H₄₅NNaO₇P

[ Molecular Weight ]:
563.662

[ Flash Point ]:
380.6±35.7 °C

[ Exact Mass ]:
563.301208

[ PSA ]:
122.85000

[ LogP ]:
6.09

[ Vapour Pressure ]:
0.0±2.4 mmHg at 25°C

[ Index of Refraction ]:
1.532

[ Storage condition ]:
-20°C Freezer

MSDS

Click to get detail MSDS

Safety Information

[ RIDADR ]:
NONH for all modes of transport

[ HS Code ]:
2933990090

Customs

[ HS Code ]: 2933990090

[ Summary ]:
2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Articles

Clopidogrel bioactivation and risk of bleeding in patients cotreated with angiotensin-converting enzyme inhibitors after myocardial infarction: a proof-of-concept study.

Clin. Pharmacol. Ther. 96(6) , 713-22, (2014)

Clopidogrel is an oral antiplatelet prodrug, the majority of which is hydrolyzed to an inactive metabolite by hepatic carboxylesterase 1 (CES1). Most angiotensin-converting enzyme inhibitors (ACEIs) a...

Fosinopril and zofenopril, two angiotensin-converting enzyme (ACE) inhibitors, potentiate the anticonvulsant activity of antiepileptic drugs against audiogenic seizures in DBA/2 mice.

Pharmacol. Res. 65(3) , 285-96, (2012)

The renin-angiotensin system (RAS) exists in the brain and it may be involved in pathogenesis of neurological and psychiatric disorders including seizures. The aim of the present research was to evalu...

Meta-analysis of randomized controlled trials on effect of angiotensin-converting enzyme inhibitors on cancer risk.

Am. J. Cardiol. 108(2) , 294-301, (2011)

The renin-angiotensin system is an important mediator of tumor progression and metastasis. A recent meta-analysis of randomized controlled trials reported an increased risk of cancer with angiotensin ...