3-(2-Fluorophenyl)-2-(methylthio)-4(3H)-pyrimidinone

Suppliers

Names

[ CAS No. ]:
89069-19-2

[ Name ]:
3-(2-Fluorophenyl)-2-(methylthio)-4(3H)-pyrimidinone

Chemical & Physical Properties

[ Density]:
1.29g/cm3

[ Boiling Point ]:
347.7ºC at 760 mmHg

[ Molecular Formula ]:
C11H9FN2OS

[ Molecular Weight ]:
236.26500

[ Flash Point ]:
164.1ºC

[ Exact Mass ]:
236.04200

[ PSA ]:
60.19000

[ LogP ]:
2.09350

[ Index of Refraction ]:
1.614

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
UW7485000
CHEMICAL NAME :
4(3H)-Pyrimidinone, 3-(2-fluorophenyl)-2-(methylthio)-
CAS REGISTRY NUMBER :
89069-19-2
LAST UPDATED :
199612
DATA ITEMS CITED :
1
MOLECULAR FORMULA :
C11-H9-F-N2-O-S
MOLECULAR WEIGHT :
236.28

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
600 mg/kg
TOXIC EFFECTS :
Behavioral - somnolence (general depressed activity) Behavioral - ataxia
REFERENCE :
IJSBDB Indian Journal of Chemistry, Section B: Organic Chemistry, Including Medicinal Chemistry. (Publications & Information Directorate, Council of Scientific and Industrial Research (CSIR), Hillside Rd., New Delhi 110 012, India) V.14B- 1976- Volume(issue)/page/year: 22,789,1983

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • N-(2-fluorophenyl)-S-methylisothiourea
  • Ethyl propiolate

DownStream

Related Compounds

  • Tert-butyl 2-[(6-chloropyridazin-3-yl)methyl]-2,7-diazaspiro[3.5]nonane-7-carboxylate
  • Tert-butyl (3aR,6aS)-2-(5-bromopyrazin-2-yl)-1,3,3a,4,6,6a-hexahydropyrrolo[3,4-c]pyrrole-5-carboxylate
  • Tert-butyl (3aS,6aR)-2-[(6-chloropyridazin-3-yl)methyl]-1,3,3a,4,6,6a-hexahydropyrrolo[3,4-c]pyrrole-5-carboxylate
  • Tert-butyl 4-[(6-chloropyridazin-3-yl)methyl-methylamino]azepane-1-carboxylate
  • Tert-butyl 3-[[(6-chloropyridazine-3-carbonyl)-methylamino]methyl]azetidine-1-carboxylate
  • Tert-butyl 3-[[(5-chloropyrazine-2-carbonyl)-methylamino]methyl]azetidine-1-carboxylate
  • Tert-butyl 8-(6-chloropyrazin-2-yl)-2,8-diazaspiro[4.5]decane-2-carboxylate
  • Tert-butyl 8-(4-chloro-1,3,5-triazin-2-yl)-2,8-diazaspiro[4.5]decane-2-carboxylate
  • Tert-butyl 8-(5-bromopyrazin-2-yl)-2,8-diazaspiro[4.5]decane-2-carboxylate
  • Tert-butyl 8-(5-chloropyrazine-2-carbonyl)-2,8-diazaspiro[4.5]decane-2-carboxylate
The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.