N-(4-Aminobutyl)-2-naphthalenesulfonamide Hydrochloride

Names

[ CAS No. ]:
89108-46-3

[ Name ]:
N-(4-Aminobutyl)-2-naphthalenesulfonamide Hydrochloride

[Synonym ]:
N-(4-aminobutyl)naphthalene-2-sulfonamide,hydrochloride
MFCD00058052

Chemical & Physical Properties

[ Boiling Point ]:
474.7ºC at 760 mmHg

[ Melting Point ]:
181-182°C

[ Molecular Formula ]:
C₁₄H₁₉ClN₂O₂S

[ Molecular Weight ]:
314.83100

[ Flash Point ]:
240.9ºC

[ Exact Mass ]:
314.08600

[ PSA ]:
80.57000

[ LogP ]:
4.83100

[ Appearance of Characters ]:
powder | yellow tan

[ Storage condition ]:
2-8°C

[ Water Solubility ]:
H2O: Stock solutions of approx. 5 mM are suggested. Stocks should be stable for at least 6 months when stored at 4?#x00b0;Csoluble

MSDS

Safety Information

[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

[ HS Code ]:
2935009090

Customs

[ HS Code ]: 2935009090

[ Summary ]:
2935009090 other sulphonamides VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:35.0%

Articles

Calmodulin and PI(3,4,5)P₃ cooperatively bind to the Itk pleckstrin homology domain to promote efficient calcium signaling and IL-17A production.

Sci. Signal. 7(337) , ra74, (2014)

Precise regulation of the kinetics and magnitude of Ca(2+) signaling enables this signal to mediate diverse responses, such as cell migration, differentiation, vesicular trafficking, and cell death. W...

N-(6-aminohexyl)-5-chloro-1-naphthalenesulfonamide, a calmodulin antagonist, inhibits cell proliferation.

Proc. Natl. Acad. Sci. U. S. A. 78 , 4354, (1981)

N-(6-Aminohexyl)-5-chloro-1-naphthalenesulfonamide (W-7) and its derivatives are putative calmodulin antagonists that bind to calmodulin and inhibit Ca2+/calmodulin-regulated enzyme activities. Autora...

A role for calcium-calmodulin in regulating nitric oxide production during skeletal muscle satellite cell activation.

Am. J. Physiol. Cell Physiol. 296 , C922-9, (2009)

When skeletal muscle is stretched or injured, myogenic satellite cells are activated to enter the cell cycle. This process depends on nitric oxide (NO) production by NO synthase (NOS), matrix metallop...

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