Atrial Natriuretic Factor (1-28) (human) acetate salt
Suppliers
Names
[ CAS No. ]:
89213-87-6
[ Name ]:
Atrial Natriuretic Factor (1-28) (human) acetate salt
[Synonym ]:
Atrial natriuretic peptide (human, 1-28)
α-Humanatrial natriuretic peptide
ANP1-28,HUMAN
HSCH2CH2(NHCO)2(CH2)2CH(CH3)2
α-ANF (1-28), human
Atrial natriuretic peptide-28 (human)
carperitide
Pentanamide,N-[[(2-mercaptoethyl)amino]carbonyl]-4-methyl
(1-28)-Human atrial natriuretic peptide
H-Ser-Leu-Arg-Arg-Ser-Ser-Cys-Phe-Gly-Gly-Arg-Met-Asp-Arg-Ile-Gly-Ala-Gln-Ser-Gly-Leu-Gly-Cys-Asn-Ser-Phe-Arg-Tyr-OH
L-seryl-L-leucyl-L-arginyl-L-arginyl-L-seryl-L-seryl-L-cysteinyl-L-phenylalanylglycylglycyl-L-arginyl-L-methionyl-L-aspartyl-L-arginyl-L-isoleucylglycyl-L-alanyl-L-glutaminyl-L-serylglycyl-L-leucylglycyl-L-cysteinyl-L-asparaginyl-L-seryl-L-phenylalanyl-L-arginyl-L-tyrosine cyclic (7->23)-disulfide
Atrial Natriuretic Peptide (1-28), human
Atrial Natriuretic Peptide (ANP) (1-28), human, porcine
Chemical & Physical Properties
[ Density]:
1.6±0.1 g/cm3
[ Molecular Formula ]:
C127H203N45O39S3
[ Molecular Weight ]:
3080.444
[ Exact Mass ]:
3078.444580
[ PSA ]:
1479.28000
[ LogP ]:
-14.30
[ Index of Refraction ]:
1.689
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- CJ9920000
- CHEMICAL NAME :
- Atriopeptin-33(rat), 1-de-L-leucine-2-de-L-alanine-3-deglycine-4-de-L-prol ine-5-de-L-arginine-1 7-L-methionine-
- CAS REGISTRY NUMBER :
- 89213-87-6
- LAST UPDATED :
- 199406
- DATA ITEMS CITED :
- 2
- MOLECULAR FORMULA :
- Cl27-H203-N45-O39-S3
- MOLECULAR WEIGHT :
- 2512.81
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Intravenous
- DOSE :
- 110 mg/kg
- SEX/DURATION :
- female 7-17 day(s) after conception
- TOXIC EFFECTS :
- Reproductive - Effects on Embryo or Fetus - fetotoxicity (except death, e.g., stunted fetus) Reproductive - Effects on Newborn - behavioral
- REFERENCE :
- OYYAA2 Oyo Yakuri. Pharmacometrics. (Oyo Yakuri Kenkyukai, CPO Box 180, Sendai 980-91, Japan) V.1- 1967- Volume(issue)/page/year: 44,495,1992
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Intravenous
- DOSE :
- 840 mg/kg
- SEX/DURATION :
- male 9 week(s) pre-mating female 2 week(s) pre-mating - 7 day(s) after conception
- TOXIC EFFECTS :
- Reproductive - Fertility - pre-implantation mortality (e.g. reduction in number of implants per female; total number of implants per corpora lutea) Reproductive - Fertility - litter size (e.g. # fetuses per litter; measured before birth)
- REFERENCE :
- OYYAA2 Oyo Yakuri. Pharmacometrics. (Oyo Yakuri Kenkyukai, CPO Box 180, Sendai 980-91, Japan) V.1- 1967- Volume(issue)/page/year: 44,485,1992