Manidipine

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Names

[ CAS No. ]:
89226-50-6

[ Name ]:
Manidipine

[Synonym ]:
2-[4-(Diphenylmethyl)-1-piperazinyl]ethylmethyl (±)-1,4-dihydro-2,6-dimethyl-4-(m-nitrophenyl)-3,5-pyridinecarboxylate
2-[4-(diphenylmethyl)piperazin-1-yl]ethyl methyl 2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate
MANIDIPINE: MANIDIPINE DIHYDROCHLORIDE
1,4-Dihydro-2,6-dimethyl-4-(3-nitrophenyl)-3,5-pyridinedicarboxylic Acid 2-[4-(Diphenylmethyl)-1-piperazinyl]ethyl Methyl Ester
1-diphenylmethyl-4-(2-hydroxyethyl)piperazine
2-[4-(Diphenylmethyl)-1-piperazinyl]ethyl methyl 2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydro-3,5-pyridinedicarboxylate
3-{2-[4-(diphenylMethyl)piperazin-1-yl]ethyl} 5-Methyl 2,6-diMethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate
Manidipine 6300
Manidipine
UNII:6O4754US88
CV-4093,2-(4-diphenylmethyl-1-piperazinyl)ethyl methyl 1,4-dihydro-2,6-dimethyl-4-(3-nitrophenyl)-3,5-pyridinedicarboxylate
Manidipine (Manyper)
2-(4-(Diphenylmethyl)-1-piperazinyl)ethyl methyl 2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate
(+/-)-1,4-dihydro-2,6-dimethyl-4-(3-nitrophenyl)-3,5-pyridinedicarboxylic acid 2-[4-(diphenylmethyl)-1-piperazinyl]ethyl methyl ester
2-(4-Diphenylmethyl-1-piperazinyl)ethyl methyl-1,4-dihydro-2,6-dimethyl-4-(3-nitrophenyl)-3,5-pyridinedicarboxylate
2-(4-benzhydryl-1-piperazinyl)ethyl methyl 2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate
Franidipine
3,5-Pyridinedicarboxylic acid, 1,4-dihydro-2,6-dimethyl-4-(3-nitrophenyl)-, 2-[4-(diphenylmethyl)-1-piperazinyl]ethyl methyl ester

Chemical & Physical Properties

[ Density]:
1.2±0.1 g/cm3

[ Boiling Point ]:
722.0±60.0 °C at 760 mmHg

[ Melting Point ]:
125-128ºC

[ Molecular Formula ]:
C35H38N4O6

[ Molecular Weight ]:
610.699

[ Flash Point ]:
390.4±32.9 °C

[ Exact Mass ]:
610.279114

[ PSA ]:
116.93000

[ LogP ]:
5.46

[ Vapour Pressure ]:
0.0±2.3 mmHg at 25°C

[ Index of Refraction ]:
1.601

[ Storage condition ]:
-20°C Freezer

Safety Information

[ Hazard Codes ]:
Xi

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • 2-(4-benzhydrylpiperazin-1-yl)ethanol
  • UNII:5DU0E310OI
  • 3-Nitrobenzaldehyde
  • 2-(4-benzhydrylpiperazin-1-yl)ethyl 3-oxobutanoate
  • Methyl 3-aminocrotonate
  • N-Benzhydrylpiperazine
  • 2-(4-diphenylmethyl-1-piperazinyl)ethyl 2-(3-nitrobenzylidene)acetoacetate

DownStream

  • Manidipine hydrochloride

Related Compounds

  • Manidipine
  • Manidipine
  • Manidipine-d4
  • (+)-manidipine
  • (-)-Manidipine
  • Manidipine 2HCl
  • 4-(chloromethyl)-3-methyl-1-(1,1,1-trifluoropropan-2-yl)-1H-pyrazole
  • tert-butyl N-[3-(3-bromoprop-1-en-2-yl)phenyl]carbamate
  • 2-chloro-N-({2-methyl-5H,6H,7H,8H-imidazo[1,2-a]pyridin-8-yl}methyl)acetamide
  • 2-chloro-N-[2-(6-oxo-1,6-dihydropyridin-3-yl)ethyl]acetamide hydrochloride
  • 3-methoxy-N-(propan-2-yl)propanehydrazide
  • 3-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)thieno[2,3-b]pyridine-2-carboxylic acid
  • N-(2-{4-[(3,4-difluorophenyl)methylidene]piperidin-1-yl}-2-oxoethyl)-N-ethylprop-2-enamide
  • 2-[ethyl({[(9H-fluoren-9-yl)methoxy]carbonyl})amino]-4-methyl-1,3-thiazole-5-carboxylic acid
  • 2-[4-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)-2H-1,2,3-triazol-2-yl]-3-methylbutanoic acid
  • 1-{[(9H-fluoren-9-yl)methoxy]carbonyl}-8-methyl-1,2,3,4-tetrahydroquinoline-6-carboxylic acid
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