Tert-butyl 8-bromo-3,4-dihydroisoquinoline-2(1H)-carboxylate

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Names

[ CAS No. ]:
893566-75-1

[ Name ]:
Tert-butyl 8-bromo-3,4-dihydroisoquinoline-2(1H)-carboxylate

[Synonym ]:
2-Methyl-2-propanyl 8-bromo-3,4-dihydro-2(1H)-isoquinolinecarboxylate
tert-butyl 8-bromo-3,4-dihydro-1H-isoquinoline-2-carboxylate
2(1H)-Isoquinolinecarboxylic acid, 8-bromo-3,4-dihydro-, 1,1-dimethylethyl ester

Chemical & Physical Properties

[ Density]:
1.4±0.1 g/cm3

[ Boiling Point ]:
382.4±42.0 °C at 760 mmHg

[ Molecular Formula ]:
C14H18BrNO2

[ Molecular Weight ]:
312.202

[ Flash Point ]:
185.0±27.9 °C

[ Exact Mass ]:
311.052094

[ PSA ]:
29.54000

[ LogP ]:
3.71

[ Vapour Pressure ]:
0.0±0.9 mmHg at 25°C

[ Index of Refraction ]:
1.559

[ Storage condition ]:
2-8°C

Safety Information

[ Hazard Codes ]:
Xi

[ HS Code ]:
2933499090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • 6-Bromo-1,2,3,4-tetrahydroisoquinoline
  • Di-tert-butyl dicarbonate
  • 8-Bromo-1,2,3,4-tetrahydroisoquinoline

DownStream

  • Tert-Butyl 6-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)-3,4-Dihydroisoquinoline-2(1H)-Carboxylate
  • 2(1H)-Isoquinolinecarboxylic acid, 3,4-dihydro-8-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-, 1,1-dimethylethyl ester

Customs

[ HS Code ]: 2933499090

[ Summary ]:
2933499090. other compounds containing in the structure a quinoline or isoquinoline ring-system (whether or not hydrogenated), not further fused. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%