2-Methyl-2-propanyl (2-oxoethyl)carbamate

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Names

[ CAS No. ]:
89711-08-0

[ Name ]:
2-Methyl-2-propanyl (2-oxoethyl)carbamate

[Synonym ]:
Carbamic acid, N-(2-oxoethyl)-, 1,1-dimethylethyl ester
t-butyl n-(2-oxoethyl)cabamate
N-tert-butoxycarbonylglycinal
tert-butyl 2-oxoethylcarbamate
2-(t-butoxycarbonylamino)acetaldehyde
N-(tert-butoxycarbonyl)-2-amino-acetaldehyde
(2-oxo-ethyl)-carbamic acid-tert-butylester
2-Methyl-2-propanyl (2-oxoethyl)carbamate
N-Boc-2-aminoacetaldehyde
N-(tert-Butoxycarbonyl)aminoacetaldehyde
boc-l-glycinal
MFCD01321273
N-tert-butyloxycarbonyl-2-aminoacetaldehyde
(tert-butoxy)-N-(2-oxoethyl)carboxamide

Chemical & Physical Properties

[ Density]:
1.0±0.1 g/cm3

[ Boiling Point ]:
237.2±23.0 °C at 760 mmHg

[ Molecular Formula ]:
C7H13NO3

[ Molecular Weight ]:
159.183

[ Flash Point ]:
97.3±22.6 °C

[ Exact Mass ]:
159.089539

[ PSA ]:
55.40000

[ LogP ]:
0.88

[ Vapour Pressure ]:
0.0±0.5 mmHg at 25°C

[ Index of Refraction ]:
1.434

MSDS

Click to get detail MSDS

Safety Information

[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ RIDADR ]:
NONH for all modes of transport

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • N-Boc-glycine N'-methoxy-N'-methylamide
  • Boc-NH-PEG1-OH
  • boc-(rs)-3-amino-1,2-propanediol
  • BOC-GLY-OME
  • tert-Butyl allylcarbamate
  • Oxalyl chloride
  • Di-tert-butyl dicarbonate
  • Potassium periodate
  • 3-BOC-amino-1,2-propanediol
  • 3-Amino-1,2-propanediol

DownStream

  • tert-Butyl prop-2-yn-1-ylcarbamate
  • 2-Butenoicacid,4-[[(1,1-dimethylethoxy)carbonyl]amino]-,(2E)-(9CI)
  • tert-butyl N-(2-hydroxypent-4-enyl)carbamate

Articles

Synthesis of fused heteroarylprolines and pyrrolopyrroles.

J. Org. Chem. 69 , 4656-4662, (2004)

Fused heteroarylprolines were prepared starting from 4-oxo-N-(PhF)proline benzyl ester (6, PhF = 9-(9-phenylfluorenyl)) following two approaches. First, allylation of oxoproline 6 followed by Wacker o...

Tumor-targeting of EGFR inhibitors by hypoxia-mediated activation.

Angew. Chem. Int. Ed. Engl. 53(47) , 12930-5, (2014)

The development of receptor tyrosine-kinase inhibitors (TKIs) was a major step forward in cancer treatment. However, the therapy with TKIs is limited by strong side effects and drug resistance. The ai...

Single cell imaging of Bruton's tyrosine kinase using an irreversible inhibitor.

Sci. Rep. 4 , 4782, (2014)

A number of Bruton's tyrosine kinase (BTK) inhibitors are currently in development, yet it has been difficult to visualize BTK expression and pharmacological inhibition in vivo in real time. We synthe...


More Articles

Related Compounds

  • 2-Methyl-2-propanyl [2-(1H-indol-3-yl)-2-oxoethyl]carbamate
  • 2-Methyl-2-propanyl [2-(5-bromo-2-pyridinyl)-2-oxoethyl]carbamate
  • tert-Butyl(2-(methylamino)-2-oxoethyl)carbamate
  • Glycine, N-[(1,1-dimethylethoxy)carbonyl]-, 2-methylhydrazide (9CI)
  • [(2,2-difluoro-ethylcarbamoyl)-methyl]-carbamic acid tert-butyl ester
  • Carbamic acid, [2-(methoxyamino)-2-oxoethyl]-, 1,1-dimethylethyl ester (9CI)