N-hydroxy-N-glucuronosyl-2-aminofluorene

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Names

[ CAS No. ]:
89947-76-2

[ Name ]:
N-hydroxy-N-glucuronosyl-2-aminofluorene

Chemical & Physical Properties

[ Molecular Formula ]:
C₁₉H₁₉NO₇

[ Molecular Weight ]:
373.35700

[ Exact Mass ]:
373.11600

[ PSA ]:
130.69000

[ LogP ]:
0.34560

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: LZ6572570

CHEMICAL NAME :: beta-D-Glucopyranuronic acid, 1-deoxy-1-(9H-fluoren-2-ylhydroxyamino)-

CAS REGISTRY NUMBER :: 89947-76-2

LAST UPDATED :: 198910

DATA ITEMS CITED :: 2

MOLECULAR FORMULA :: C19-H19-N-O7

MOLECULAR WEIGHT :: 373.39

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Parenteral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 5600 ug/kg/30W-C

TOXIC EFFECTS :: Tumorigenic - Carcinogenic by RTECS criteria Kidney, Ureter, Bladder - tumors

MUTATION DATA

TYPE OF TEST :: Unscheduled DNA synthesis

TEST SYSTEM :: Human Cells - not otherwise specified

DOSE/DURATION :: 100 nmol/L

REFERENCE :: JJIND8 JNCI, Journal of the National Cancer Institute. (Washington, DC) V.61-79, 1978-87. For publisher information, see JNCIEQ. Volume(issue)/page/year: 72,847,1984

Related Compounds

N-hydroxy-N-(2-methoxyphenyl)benzamide
N-hydroxy-N-(2-phenylethyl)-1-phenylethanamine
N-hydroxy-N-(2-methylphenyl)benzenecarboximidamide
N-hydroxy-N-(2-methylphenyl)-N-phenyl-benzenecarboximidamide
2-acetylaminofluorene-N-sulfate
Urea,N-hydroxy-N-[2-(1H-imidazol-4-yl)ethyl]- (9CI)