2-Cyanoethyl diisopropylamidochlorophosphite

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Names

[ Name ]:
2-Cyanoethyl diisopropylamidochlorophosphite

[Synonym ]:
Phosphoramidochloridous acid, N,N-bis(1-methylethyl)-, 2-cyanoethyl ester
2-CYANOETHYL N,N-DIISOPROPYLCHLOROPHOSPHORAMIDITE
2-cyanoethyl dipropan-2-ylphosphoramidochloridoite
2-Cyanoethyldiisopropylchlorophosphoramidite
2-Cyanoethyl diisopropylphosphoramidochloridoite
2-Cyanoethyl diisopropylamidochlorophosphite
MFCD00011544
3-[chloro-[di(propan-2-yl)amino]phosphanyl]oxypropanenitrile

Chemical & Physical Properties

[ Density]:
1.061 g/mL at 25 °C(lit.)

[ Boiling Point ]:
343.8±0.0 °C at 760 mmHg

[ Molecular Formula ]:
C₉H₁₈ClN₂OP

[ Molecular Weight ]:
236.679

[ Flash Point ]:
135.8±28.4 °C

[ Exact Mass ]:
236.084534

[ PSA ]:
49.85000

[ LogP ]:
3.46

[ Vapour Pressure ]:
0.0±0.7 mmHg at 25°C

[ Index of Refraction ]:
n20/D 1.479

[ Storage condition ]:
−20°C

MSDS

Click to get detail MSDS

Safety Information

[ Symbol ]:

GHS02, GHS05

[ Signal Word ]:
Danger

[ Hazard Statements ]:
H250-H314

[ Precautionary Statements ]:
P222-P231-P280-P305 + P351 + P338-P310-P422

[ Personal Protective Equipment ]:
Faceshields;full-face respirator (US);Gloves;Goggles;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter

[ Hazard Codes ]:
C:Corrosive;

[ Risk Phrases ]:
R20/21/22;R29;R34;R5

[ Safety Phrases ]:
S26-S36/37/39-S45-S8

[ RIDADR ]:
UN 2845 4.2/PG 1

[ WGK Germany ]:
3

[ Packaging Group ]:
II

[ Hazard Class ]:
8

Articles

Synthesis of non-natural sequence-encoded polymers using phosphoramidite chemistry.

J. Am. Chem. Soc. 137 , 5629-35, (2015)

Sequence-defined non-natural polyphosphates were prepared using iterative phosphoramidite protocols on a polystyrene solid support. Three monomers were used in this work: 2-cyanoethyl (3-dimethoxytrit...

Proteomic-based approach to gain insight into reprogramming of THP-1 cells exposed to Leishmania donovani over an early temporal window.

Bioconjug. Chem. 4 , 499, (1993)

Leishmania donovani, a protozoan parasite, is the causative agent of visceral leishmaniasis. It lives and multiplies within the harsh environment of macrophages. In order to investigate how intracellu...

Solid-phase reagents for selective monophosphorylation of carbohydrates and nucleosides.

J. Org. Chem. 70(3) , 1100-3, (2005)

Two classes of aminomethyl polystyrene resin-bound linkers of p-acetoxybenzyl alcohol were subjected to reactions with 2-cyanoethyl N,N-diisopropylchlorophosphoramidite to produce the corresponding po...

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