Pheneturide

Suppliers

Names

[ CAS No. ]:
90-49-3

[ Name ]:
Pheneturide

[Synonym ]:
Lircapyl
Phenuride
ETHYLPHENACEMIDE
PBU
EINECS 201-998-2
S 46
PHENETURIDE
Benuride
MFCD00069050

Chemical & Physical Properties

[ Density]:
1.15g/cm3

[ Melting Point ]:
149.5 °C

[ Molecular Formula ]:
C11H14N2O2

[ Molecular Weight ]:
206.24100

[ Exact Mass ]:
206.10600

[ PSA ]:
72.19000

[ LogP ]:
2.46630

[ Index of Refraction ]:
1.547

MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
YU1225000
CHEMICAL NAME :
Urea, (2-phenylbutyryl)-
CAS REGISTRY NUMBER :
90-49-3
LAST UPDATED :
199309
DATA ITEMS CITED :
5
MOLECULAR FORMULA :
C11-H14-N2-O2
MOLECULAR WEIGHT :
206.27
WISWESSER LINE NOTATION :
ZVMVY2&R

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
>2063 mg/kg
TOXIC EFFECTS :
Behavioral - somnolence (general depressed activity)
REFERENCE :
ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag, Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951- Volume(issue)/page/year: 18,524,1968
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
910 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
NIIRDN Drugs in Japan (Ethical Drugs). (Yakugyo Jiho Co., Ltd., Tokyo, Japan) Volume(issue)/page/year: 6,114,1982
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
312 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
THERAP Therapie. (Doin, Editeurs, 8, Place de l'Odeon, F-75006 Paris, France) V.1- 1946- Volume(issue)/page/year: 22,641,1967
TYPE OF TEST :
LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rabbit
DOSE/DURATION :
1 gm/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. (Heymans Institute of Pharmacology, De Pintelaan 185, B-9000 Ghent, Belgium) V.4- 1898- Volume(issue)/page/year: 91,437,1952
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - guinea pig
DOSE/DURATION :
641 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. (Heymans Institute of Pharmacology, De Pintelaan 185, B-9000 Ghent, Belgium) V.4- 1898- Volume(issue)/page/year: 91,437,1952

Safety Information

[ Hazard Codes ]:
Xi

[ RIDADR ]:
UN 3249

[ Packaging Group ]:
III

[ Hazard Class ]:
6.1(b)

Synthetic Route

Precursor & DownStream

Precursor

  • 2-Phenylbutyryl chloride
  • Urea
  • Benzobarbital
  • phenobarbital
  • carbonyl diisocyanate
  • UNII:S7S079H2C2
  • Water
  • phenobarbital sodium

DownStream


Related Compounds

  • PHENETURIDE