tris(Dimethylaminomethyl)phenol

Names

[ CAS No. ]:
90-72-2

[ Name ]:
tris(Dimethylaminomethyl)phenol

[Synonym ]:
Phenol, 2,4,6-tris[(dimethylamino)methyl]-
tris(Dimethylaminomethyl)phenol
2,4,6-Tris[(dimethylamino)methyl]phenol
MFCD00008330
EINECS 202-013-9

Chemical & Physical Properties

[ Density]:
1.0±0.1 g/cm3

[ Boiling Point ]:
320.5±0.0 °C at 760 mmHg

[ Molecular Formula ]:
C₁₅H₂₇N₃O

[ Molecular Weight ]:
265.394

[ Flash Point ]:
116.6±25.2 °C

[ Exact Mass ]:
265.215424

[ PSA ]:
29.95000

[ LogP ]:
0.76

[ Vapour density ]:
>1 (vs air)

[ Vapour Pressure ]:
0.0±0.7 mmHg at 25°C

[ Index of Refraction ]:
1.548

[ Storage condition ]:
2-8°C

MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: SN3500000

CHEMICAL NAME :: Phenol, 2,4,6-tris(dimethylaminomethyl)-

CAS REGISTRY NUMBER :: 90-72-2

BEILSTEIN REFERENCE NO. :: 0795751

LAST UPDATED :: 199803

DATA ITEMS CITED :: 9

MOLECULAR FORMULA :: C15-H27-N3-O

MOLECULAR WEIGHT :: 265.45

WISWESSER LINE NOTATION :: 1N1&1R BQ C1N1&1 E1N1&1

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: Standard Draize test

ROUTE OF EXPOSURE :: Administration onto the skin

SPECIES OBSERVED :: Rodent - rabbit

REFERENCE :: 85JCAE "Prehled Prumyslove Toxikologie; Organicke Latky," Marhold, J., Prague, Czechoslovakia, Avicenum, 1986 Volume(issue)/page/year: -,699,1986

TYPE OF TEST :: Standard Draize test

ROUTE OF EXPOSURE :: Administration into the eye

SPECIES OBSERVED :: Rodent - rabbit

REFERENCE :: 85JCAE "Prehled Prumyslove Toxikologie; Organicke Latky," Marhold, J., Prague, Czechoslovakia, Avicenum, 1986 Volume(issue)/page/year: -,699,1986 ** ACUTE TOXICITY DATA **

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 1200 mg/kg

TOXIC EFFECTS :: Peripheral Nerve and Sensation - flaccid paralysis without anesthesia (usually neuromuscular blockage) Lungs, Thorax, or Respiration - dyspnea

REFERENCE :: RPTOAN Russian Pharmacology and Toxicology (English Translation). Translation of FATOAO. (Euromed Pub., 33, Woodlands Rd., Surbiton, Surrey, UK) V.30- 1967- Volume(issue)/page/year: 37,130,1974

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Administration onto the skin

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 1280 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: ROHM** Rohm and Haas Company Data Sheets. (Philadelphia, PA 19105) *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - M1312 No. of Facilities: 595 (estimated) No. of Industries: 13 No. of Occupations: 18 No. of Employees: 9751 (estimated) NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - M1312 No. of Facilities: 4775 (estimated) No. of Industries: 63 No. of Occupations: 65 No. of Employees: 100136 (estimated) No. of Female Employees: 15210 (estimated)

Safety Information

[ Symbol ]:

GHS05, GHS07

[ Signal Word ]:
Danger

[ Hazard Statements ]:
H314-H317-H412

[ Precautionary Statements ]:
P273-P280-P305 + P351 + P338-P310

[ Personal Protective Equipment ]:
Faceshields;full-face respirator (US);Gloves;Goggles;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter

[ Hazard Codes ]:
Xn:Harmful;

[ Risk Phrases ]:
R22;R36/38

[ Safety Phrases ]:
S26-S28-S2

[ RIDADR ]:
UN 2735 8/PG 3

[ WGK Germany ]:
1

[ RTECS ]:
SN3500000

[ Packaging Group ]:
III

[ Hazard Class ]:
8

[ HS Code ]:
29222900

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

Formaldehyde
Dimethylamine
Phenol
4-Hydroxybenzoic acid
Water

DownStream

Customs

[ HS Code ]: 29222900

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