trypsinogen

Names

[ CAS No. ]:
9002-08-8

[ Name ]:
trypsinogen

[Synonym ]:
EINECS 232-651-3
Trypsinogen,PMSF treated from bovine pancreas
MFCD00466939
trypsinogen from bovine pancreas

Chemical & Physical Properties

[ Molecular Formula ]:
C39H55N9O17

[ Molecular Weight ]:
921.90400

[ Exact Mass ]:
921.37200

[ PSA ]:
433.45000

Safety Information

[ Symbol ]:

GHS08

[ Signal Word ]:
Danger

[ Hazard Statements ]:
H315-H319-H334

[ Precautionary Statements ]:
P261-P305 + P351 + P338-P342 + P311

[ Personal Protective Equipment ]:
Eyeshields;Faceshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ Hazard Codes ]:
Xn: Harmful;

[ Risk Phrases ]:
36/37/38-42

[ Safety Phrases ]:
22-24-26-36/37

[ RIDADR ]:
NONH for all modes of transport

Articles

Leukocyte protease binding to nucleic acids promotes nuclear localization and cleavage of nucleic acid binding proteins.

J. Immunol. 192(11) , 5390-7, (2014)

Killer lymphocyte granzyme (Gzm) serine proteases induce apoptosis of pathogen-infected cells and tumor cells. Many known Gzm substrates are nucleic acid binding proteins, and the Gzms accumulate in t...

Long-range electrostatic complementarity governs substrate recognition by human chymotrypsin C, a key regulator of digestive enzyme activation.

J. Biol. Chem. 288(14) , 9848-59, (2013)

Human chymotrypsin C (CTRC) is a pancreatic serine protease that regulates activation and degradation of trypsinogens and procarboxypeptidases by targeting specific cleavage sites within their zymogen...

Robust autoactivation, chymotrypsin C independence and diminished secretion define a subset of hereditary pancreatitis-associated cationic trypsinogen mutants.

FEBS J. 280(12) , 2888-99, (2013)

Mutations in human cationic trypsinogen cause hereditary pancreatitis by altering its proteolytic regulation of activation and degradation by chymotrypsin C (CTRC). CTRC stimulates trypsinogen autoact...


More Articles

Related Compounds

  • trypsinogen 2
  • trypsinogen III
  • 2-[[5-(4-Bromophenyl)-4-cyclohexyl-4H-1,2,4-triazol-3-yl]thio]-N-[2-(4-morpholinyl)-5-(trifluoromethyl)phenyl]acetamide
  • 2-Phenylpyrazolo[1,5-a]pyrimidine
  • Acetonitrile, 2-[(3,4-dimethoxyphenyl)amino]-
  • (4R)-N-Octadecyl-2-phenyl-4-thiazolidinecarboxamide
  • 8-Amino-6-(furan-3-yl)-4-oxo-9-oxa-12-thia-3,14-diazapentacyclo[11.9.0.02,11.05,10.015,21]docosa-1(13),2(11),5(10),7,14,21-hexaene-7-carbonitrile
  • 1-(Methylamino)cyclohexaneethanamine
  • 2-(4-Fluorostyryl)-3-phenyl-5-(phenylamino)-1,3,4-thiadiazol-3-ium chloride
  • 4-(2-(7-(4-methoxyphenyl)-2-methyl-4-oxothiazolo[4,5-d]pyridazin-5(4H)-yl)acetamido)benzamide
  • (I+/-R)-I+/--[(1S)-1-(Formylhydroxyamino)-2-methylpropyl]-N-[(1S)-4-[[imino[(2-pyridinylsulfonyl)amino]methyl]amino]-1-[(2-thiazolylamino)carbonyl]butyl]-4-methylcyclohexanepropanamide
  • 1-[3-(Octyloxy)phenyl]ethanone
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