Polyethylene-polypropylene glycol

Suppliers

Names

[ Name ]:
Polyethylene-polypropylene glycol

[Synonym ]:
3-Acetoxy-2,2-bis(acetoxymethyl)propyl acetate
Poloxamer 407
MFCD00082049
Pentaerythrityl Tetraacetate
PAG
Poloxamer
2,2-Bis[(acetyloxy)methyl]-1,3-propanediol Diacetate
1,3-Propanediol, 2,2-bis[(acetyloxy)methyl]-, diacetate
Poly(ethylene glycol)-block-poly(propylene glycol)-block-poly(ethylene glycol)
Tetra-O-acetylpentaerythritol
pentaerythritol tetraacetate

Chemical & Physical Properties

[ Density]:
1.2±0.1 g/cm3

[ Boiling Point ]:
370.7±37.0 °C at 760 mmHg

[ Melting Point ]:
60-50ºC

[ Molecular Formula ]:
C₁₃H₂₀O₈

[ Molecular Weight ]:
304.293

[ Flash Point ]:
160.5±26.5 °C

[ Exact Mass ]:
304.115814

[ PSA ]:
25.06000

[ LogP ]:
0.00

[ Vapour density ]:
>1 (vs air)

[ Vapour Pressure ]:
0.0±0.8 mmHg at 25°C

[ Index of Refraction ]:
1.452

[ Storage condition ]:
2-8°C

[ Water Solubility ]:
H2O: at <70 °Csoluble

MSDS

Click to get detail MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: TP6000000

CHEMICAL NAME :: Pluronic F98

CAS REGISTRY NUMBER :: 9003-11-6

LAST UPDATED :: 199710

DATA ITEMS CITED :: 7

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 175 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: MIVRA6 Microvascular Research. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1968- Volume(issue)/page/year: 8,320,1974 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - M3966 No. of Facilities: 6846 (estimated) No. of Industries: 44 No. of Occupations: 37 No. of Employees: 38016 (estimated) NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - X7313 No. of Facilities: 59555 (estimated) No. of Industries: 299 No. of Occupations: 176 No. of Employees: 1005983 (estimated) No. of Female Employees: 296376 (estimated)

Safety Information

[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ Hazard Codes ]:
T

[ Risk Phrases ]:
21-23/24/25-25-36/37/38

[ Safety Phrases ]:
23-24/25-45-36/37/39-26

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

[ RTECS ]:
TP6164333

[ HS Code ]:
39059100

Articles

Uniaxial repetitive mechanical overloading induces influx of extracellular calcium and cytoskeleton disruption in human tenocytes.

Cell Tissue Res. 359(2) , 577-87, (2015)

Tendon calcification is common in the Achilles tendon, and injuries affect not only athletes, but also the general population. However, the underlying cellular mechanisms are not yet fully understood....

Microtubule plus-end tracking by CLIP-170 requires EB1.

Proc. Natl. Acad. Sci. U. S. A. 106 , 492-7, (2009)

Microtubules are polarized polymers that exhibit dynamic instability, with alternating phases of elongation and shortening, particularly at the more dynamic plus-end. Microtubule plus-end tracking pro...

Zinc oxide nanoparticles as selective killers of proliferating cells.

Int. J. Nanomedicine 6 , 1129-40, (2011)

It has recently been demonstrated that zinc oxide nanoparticles (ZnO NPs) induce death of cancerous cells whilst having no cytotoxic effect on normal cells. However, there are several issues which nee...

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