Polyvinylpyrrolidone

Suppliers

Names

[ CAS No. ]:
9003-39-8

[ Name ]:
Polyvinylpyrrolidone

[Synonym ]:
k60
Polyvinylpyrrolidone
PVP
Kollidon K25
Kollidon K-90
k25
MFCD00149016
POP
Kollidon 25
k115
pvp2
pvp3
K-30
pvp4
PVPD

Chemical & Physical Properties

[ Density]:
1.144g/cm3

[ Boiling Point ]:
217.6ºC at 760 mmHg

[ Melting Point ]:
130ºC

[ Molecular Formula ]:
(C6H9NO)n

[ Molecular Weight ]:
111.1418 (monomer)

[ Flash Point ]:
93.9ºC

[ PSA ]:
20.31000

[ LogP ]:
0.69020

[ Storage condition ]:
Store at RT.

[ Water Solubility ]:
H2O: soluble100mg/mL

MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
TR8300000
CHEMICAL NAME :
Poly(1-vinyl-2-pyrrolidinone) Hueper's Polymer No.5
CAS REGISTRY NUMBER :
9003-39-8
LAST UPDATED :
199710
DATA ITEMS CITED :
9
WISWESSER LINE NOTATION :
/T5NVTJ AY*1*/

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
2500 mg/kg
TOXIC EFFECTS :
Tumorigenic - Carcinogenic by RTECS criteria Liver - tumors Endocrine - tumors
REFERENCE :
AMPLAO AMA Archives of Pathology. (Chicago, IL) V.50(4)-69, 1950-60. For publisher information, see APLMAS. Volume(issue)/page/year: 67,589,1959
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Subcutaneous
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
2500 mg/kg
TOXIC EFFECTS :
Tumorigenic - Carcinogenic by RTECS criteria Liver - tumors Reproductive - Tumorigenic effects - uterine tumors
REFERENCE :
AMPLAO AMA Archives of Pathology. (Chicago, IL) V.50(4)-69, 1950-60. For publisher information, see APLMAS. Volume(issue)/page/year: 67,589,1959
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
8000 mg/kg
TOXIC EFFECTS :
Tumorigenic - equivocal tumorigenic agent by RTECS criteria Cardiac - tumors Endocrine - tumors
REFERENCE :
AMPLAO AMA Archives of Pathology. (Chicago, IL) V.50(4)-69, 1950-60. For publisher information, see APLMAS. Volume(issue)/page/year: 67,589,1959 *** REVIEWS *** IARC Cancer Review:Animal Limited Evidence IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) V.1- 1972- Volume(issue)/page/year: 19,461,1979 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - 81235 No. of Facilities: 7856 (estimated) No. of Industries: 50 No. of Occupations: 63 No. of Employees: 102100 (estimated) NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - X7211 No. of Facilities: 7688 (estimated) No. of Industries: 46 No. of Occupations: 63 No. of Employees: 161259 (estimated) No. of Female Employees: 84819 (estimated)

Safety Information

[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ Hazard Codes ]:
Xn

[ Safety Phrases ]:
S24/25

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
1

[ RTECS ]:
TR8370000

[ HS Code ]:
3905990000

Synthetic Route

Precursor & DownStream

Precursor

  • 3-Vinyl-2-pyrrolidinone

DownStream

Customs

[ HS Code ]: 3905990000

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Related Compounds

  • polyvinylpyrrolidone
  • Polyvinylpyrrolidone
  • gossypol-polyvinylpyrrolidone
  • Polyvinylpyrrolidone-formaldehyde
  • Polyvinylpyrrolidone-Iodine Complex
  • Polyvinylpyrrolidone-o-phenylphenol
  • 3-(2-Methoxyethyl)-2,4-dioxo-1,3-diazaspiro[4.5]decane-8-carboxylic acid
  • Methyl 3-ethyl-2,4-dioxo-1,3-diazaspiro[4.5]decane-8-carboxylate
  • Ethyl 5-cyclopropyl-7-hydroxypyrazolo[1,5-a]pyrimidine-3-carboxylate
  • 2-(3-(Methylcarbamoyl)-6-oxo-5,6-dihydropyridazin-1(4H)-yl)acetic acid
  • 2-(3-(Ethylcarbamoyl)-6-oxo-5,6-dihydropyridazin-1(4H)-yl)aceticacid
  • 2-(3-(Cyclopropylcarbamoyl)-6-oxo-5,6-dihydropyridazin-1(4H)-yl)acetic acid
  • 2-(6-Oxo-3-(pyrrolidine-1-carbonyl)-5,6-dihydropyridazin-1(4H)-yl)acetic acid
  • 1-(Cyclopropylmethyl)-6-oxo-1,6-dihydropyridazine-3-carboxylic acid
  • 2-(3-(Methylcarbamoyl)-6-oxopyridazin-1(6H)-yl)acetic acid
  • 2-(3-(Dimethylcarbamoyl)-6-oxopyridazin-1(6H)-yl)acetic acid
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