Native Aspergillus melleus Acylase I

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Names

[ Name ]:
Native Aspergillus melleus Acylase I

[Synonym ]:
7-[(6,8-Dichloro-1,2,3,4-tetrahydro-9-acridinyl)amino]-N-[2-(1H-indol-3-yl)ethyl]heptanamide
E.C. 3.5.1.14
N-Acyl-L-amino acid amidohydrolase
Hippuricase
Benzamidase
Dehydropeptidase II
Aminoacylase I
Histozyme
Hippurase
L-Aminoacylase
7-[(6,8-dichloro-1,2,3,4-tetrahydroacridin-9-yl)amino]-N-[2-(1H-indol-3-yl)ethyl]heptanamide
Amino acid deacylase
Aminoacylase 1
L-Amino acid acylase
Acylase 1500 Amano
MFCD00081285
Heptanamide, 7-[(6,8-dichloro-1,2,3,4-tetrahydro-9-acridinyl)amino]-N-[2-(1H-indol-3-yl)ethyl]-
Acylase I
EINECS 232-732-3
Acylase
Native Aspergillus melleus Acylase I

Chemical & Physical Properties

[ Density]:
1.3±0.1 g/cm3

[ Boiling Point ]:
813.3±65.0 °C at 760 mmHg

[ Molecular Formula ]:
C₃₀H₃₄Cl₂N₄O

[ Molecular Weight ]:
537.523

[ Flash Point ]:
445.7±34.3 °C

[ Exact Mass ]:
536.210938

[ LogP ]:
7.64

[ Vapour Pressure ]:
0.0±2.9 mmHg at 25°C

[ Index of Refraction ]:
1.668

Safety Information

[ Symbol ]:

GHS07, GHS08

[ Signal Word ]:
Danger

[ Hazard Statements ]:
H315-H319-H334-H335

[ Precautionary Statements ]:
P261-P305 + P351 + P338-P342 + P311

[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ Hazard Codes ]:
Xn

[ Risk Phrases ]:
36/37/38-42

[ Safety Phrases ]:
22-24/25

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

[ RTECS ]:
BF4890000

Articles

Structure of a class III engineered cephalosporin acylase: comparisons with class I acylase and implications for differences in substrate specificity and catalytic activity.

Biochem. J. 451(2) , 217-26, (2013)

The crystal structure of the wild-type form of glutaryl-7-ACA (7-aminocephalosporanic acid) acylase from Pseudomonas N176 and a double mutant of the protein (H57βS/H70βS) that displays enhanced cataly...

Disposition of bisphenol AF, a bisphenol A analogue, in hepatocytes in vitro and in male and female Harlan Sprague-Dawley rats and B6C3F1/N mice following oral and intravenous administration.

Xenobiotica 45 , 811-9, (2015)

1. Bisphenol AF (BPAF) is used as a crosslinking agent for polymers and is being considered as a replacement for bisphenol A (BPA). 2. In this study, comparative clearance and metabolism of BPAF and B...

Hydrolysis of N-acyl derivatives of alanine and phenylalanine by acylase I and carboxypeptidase.

J. Biol. Chem. 201(2) , 847-56, (1953)

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