Pyruvate Dehydrogenase

[ Density]:
1.3±0.1 g/cm3

[ Boiling Point ]:
508.4±50.0 °C at 760 mmHg

[ Molecular Formula ]:
C₁₇H₁₅NO₄

[ Molecular Weight ]:
297.305

[ Flash Point ]:
261.3±30.1 °C

[ Exact Mass ]:
297.100098

[ LogP ]:
3.66

[ Vapour Pressure ]:
0.0±1.3 mmHg at 25°C

[ Index of Refraction ]:
1.611

[ Storage condition ]:
-20°C

[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ Risk Phrases ]:
23-24/25

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

Alternating sites reactivity is a common feature of thiamin diphosphate-dependent enzymes as evidenced by isothermal titration calorimetry studies of substrate binding.

Biochemistry 52(15) , 2505-7, (2013)

Thiamin diphosphate (ThDP)-dependent enzymes play vital roles in cellular metabolism in all kingdoms of life. In previous kinetic and structural studies, a communication between the active centers in ...

Enhanced glucose metabolism is preserved in cultured primary myotubes from obese donors in response to exercise training.

J. Clin. Endocrinol. Metab. 98(9) , 3739-47, (2013)

It was suggested that human cultured primary myotubes retain the metabolic characteristics of their donor in vitro.The aim of the present study was to investigate whether the metabolic responses to en...

Intermittent-relapsing pyruvate dehydrogenase complex deficiency: a case with clinical, biochemical, and neuroradiological reversibility.

Dev. Med. Child Neurol. 54(5) , 472-6, (2012)

Pyruvate dehydrogenase complex (PDHC) deficiency causes encephalomyopathies, of which there are four major categories: (1) neonatal encephalopathy with lactic acidosis; (2) an early infantile form, wh...

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