Polymethylene polyphenyl polyisocyanate
Suppliers
Names
[ CAS No. ]:
9016-87-9
[ Name ]:
Polymethylene polyphenyl polyisocyanate
[Synonym ]:
N,N'''-1,6-Hexanediylbis(N'-cyanoguanidine),hexamethylenediamine polymer,hydrochloride
4,4′-Methylenebis(phenyl isocyanate)
4,4'-Methylenediphenyl diisocyanate
4,4'-Methylenebis(phenyl isocyanate)
diphenylmethane-4,4'-diisocyanate
Poly(hexamethylenebicyanoguanide-hexamethylenediamine) hydrochloride
PMDI
bis(4-isocyanatophenyl)methane
1,1'-methanediylbis(4-isocyanatobenzene)
polymeric diisocyanatodiphenylmethane
MFCD00072953
4,4'-Diphenylmethane diisocyanate
2,2'-hexane-1,6-diylbis(1-cyanoguanidine)-hexane-1,6-diamine hydrochloride(1:1:1)
1,1'-Methylenebis(4-isocyanatobenzene)
4,4'-MDI
polymeric biguanidin hydrochloride
1,6-Hexanediamine,polymer with N,N'''-1,6-hexanediylbis(N'-cyanoguanidine),hydrochloride
4,4'-Methylenediphenyl isocyanate
4,4'-Diisocyanatodiphenylmethane
4,4'-methylene bisphenyl diisocyanate
Benzene, 1,1'-methylenebis[4-isocyanato-
Methylene diphenyl diisocyanate
Polymethylene polyphenyl polyisocyanate
Chemical & Physical Properties
[ Density]:
1.1±0.1 g/cm3
[ Boiling Point ]:
373.4±35.0 °C at 760 mmHg
[ Molecular Formula ]:
C15H10N2O2
[ Molecular Weight ]:
250.252
[ Flash Point ]:
154.0±31.3 °C
[ Exact Mass ]:
250.074234
[ PSA ]:
58.86000
[ LogP ]:
4.93
[ Vapour density ]:
8.6 (vs air)
[ Vapour Pressure ]:
0.0±0.8 mmHg at 25°C
[ Index of Refraction ]:
1.588
[ Stability ]:
Stable. Incompatible with strong oxidizing agents, alcohols. May decompose in moist air, or on contact with water.
MSDS
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- TR0350000
- CHEMICAL NAME :
- Polymethylenepolyphenyl isocyanate
- CAS REGISTRY NUMBER :
- 9016-87-9
- LAST UPDATED :
- 199710
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- Standard Draize test
- ROUTE OF EXPOSURE :
- Administration into the eye
- SPECIES OBSERVED :
- Rodent - rabbit
- REFERENCE :
- NTIS** National Technical Information Service. (Springfield, VA 22161) Formerly U.S. Clearinghouse for Scientific & Technical Information. Volume(issue)/page/year: OTS0516728 ** ACUTE TOXICITY DATA **
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 49 gm/kg
- TOXIC EFFECTS :
- Behavioral - somnolence (general depressed activity) Gastrointestinal - hypermotility, diarrhea Nutritional and Gross Metabolic - body temperature decrease
- REFERENCE :
- NTIS** National Technical Information Service. (Springfield, VA 22161) Formerly U.S. Clearinghouse for Scientific & Technical Information. Volume(issue)/page/year: OTS0516728
- TYPE OF TEST :
- LC50 - Lethal concentration, 50 percent kill
- ROUTE OF EXPOSURE :
- Inhalation
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 490 mg/m3/4H
- TOXIC EFFECTS :
- Sense Organs and Special Senses (Eye) - effect, not otherwise specified Lungs, Thorax, or Respiration - respiratory depression Blood - hemorrhage
- REFERENCE :
- NTIS** National Technical Information Service. (Springfield, VA 22161) Formerly U.S. Clearinghouse for Scientific & Technical Information. Volume(issue)/page/year: OTS0555284
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Administration onto the skin
- SPECIES OBSERVED :
- Rodent - rabbit
- DOSE/DURATION :
- >9400 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- TSCAT* Office of Toxic Substances Report. (U.S. Environmental Protection Agency, Office of Toxic Substances, 401 M St., SW, Washington, DC 20460) Volume(issue)/page/year: OTS0517028 ** OTHER MULTIPLE DOSE TOXICITY DATA **
- TYPE OF TEST :
- TCLo - Lowest published toxic concentration
- ROUTE OF EXPOSURE :
- Inhalation
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 15 mg/m3/2W-I
- TOXIC EFFECTS :
- Lungs, Thorax, or Respiration - changes in lung weight Nutritional and Gross Metabolic - weight loss or decreased weight gain Related to Chronic Data - death
- REFERENCE :
- NTIS** National Technical Information Service. (Springfield, VA 22161) Formerly U.S. Clearinghouse for Scientific & Technical Information. Volume(issue)/page/year: OTS0525557
- TYPE OF TEST :
- TCLo - Lowest published toxic concentration
- ROUTE OF EXPOSURE :
- Inhalation
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 12 mg/m3/13W-I
- TOXIC EFFECTS :
- Related to Chronic Data - death
- REFERENCE :
- NTIS** National Technical Information Service. (Springfield, VA 22161) Formerly U.S. Clearinghouse for Scientific & Technical Information. Volume(issue)/page/year: OTS0525557 ** TUMORIGENIC DATA **
- TYPE OF TEST :
- TCLo - Lowest published toxic concentration
- ROUTE OF EXPOSURE :
- Inhalation
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 6 mg/m3/6H/2Y-I
- TOXIC EFFECTS :
- Tumorigenic - equivocal tumorigenic agent by RTECS criteria Lungs, Thorax, or Respiration - tumors
- REFERENCE :
- NTIS** National Technical Information Service. (Springfield, VA 22161) Formerly U.S. Clearinghouse for Scientific & Technical Information. Volume(issue)/page/year: OTS0525557 *** REVIEWS *** IARC Cancer Review:Human No Adequate Data IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) V.1- 1972- Volume(issue)/page/year: 19,303,1979 IARC Cancer Review:Animal No Adequate Data IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) V.1- 1972- Volume(issue)/page/year: 19,303,1979 IARC Cancer Review:Group 3 IMSUDL IARC Monographs, Supplement. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) No.1- 1979- Volume(issue)/page/year: 7,56,1987 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - 84716 No. of Facilities: 367 (estimated) No. of Industries: 10 No. of Occupations: 14 No. of Employees: 2795 (estimated) NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - 84716 No. of Facilities: 2951 (estimated) No. of Industries: 59 No. of Occupations: 48 No. of Employees: 45703 (estimated) No. of Female Employees: 6250 (estimated)
Safety Information
[ Symbol ]:
GHS07, GHS08
[ Signal Word ]:
Danger
[ Hazard Statements ]:
H315-H317-H319-H332-H334-H335-H351-H373
[ Precautionary Statements ]:
P260-P280-P284-P304 + P340-P305 + P351 + P338-P342 + P311
[ Hazard Codes ]:
Xn: Harmful;
[ Risk Phrases ]:
R20
[ Safety Phrases ]:
S26;S28;S38;S45
[ RIDADR ]:
NONH for all modes of transport
[ WGK Germany ]:
3
[ RTECS ]:
TR0350000
[ Packaging Group ]:
II
[ Hazard Class ]:
6.1
[ HS Code ]:
3909301000
Customs
[ HS Code ]: 3909301000
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