Carboxypeptidase B

[ Density]:
1.3±0.1 g/cm3

[ Boiling Point ]:
966.7±65.0 °C at 760 mmHg

[ Molecular Formula ]:
C₃₁H₃₈N₄O₇S

[ Molecular Weight ]:
610.721

[ Flash Point ]:
538.4±34.3 °C

[ Exact Mass ]:
610.246094

[ PSA ]:
197.75000

[ LogP ]:
3.26

[ Vapour Pressure ]:
0.0±0.3 mmHg at 25°C

[ Index of Refraction ]:
1.595

[ Storage condition ]:
−20°C

Click to get detail MSDS

[ Symbol ]:

GHS07, GHS08

[ Signal Word ]:
Danger

[ Hazard Statements ]:
H315-H319-H334-H335

[ Precautionary Statements ]:
P261-P305 + P351 + P338-P342 + P311

[ Personal Protective Equipment ]:
Eyeshields;Gloves

[ Hazard Codes ]:
Xi: Irritant;

[ Risk Phrases ]:
36

[ Safety Phrases ]:
26-36

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

Effects of citraconylation on enzymatic modification of human proinsulin using trypsin and carboxypeptidase B.

Biotechnol. Prog. 25(4) , 1064-70, (2009)

Insulin is a polypeptide hormone which is produced by the beta-cell of pancreas and controls the blood glucose level in the human body. Enzymatic modification of human proinsulin using trypsin and car...

Comparative study on activation mechanism of carboxypeptidase A1, A2 and B: First insights from steered molecular dynamics simulations

J. Mol. Graph. Model. 38 , 298-303, (2012)

Graphical abstract

Structural basis for inhibition of carboxypeptidase B by selenium-containing inhibitor: selenium coordinates to zinc in enzyme.

J. Med. Chem. 56(19) , 7527-35, (2013)

Activated thrombin-activatable fibrinolysis inhibitor (TAFIa) is a zinc-containing carboxypeptidase and significantly inhibits fibrinolysis. TAFIa inhibitors are thus expected to act as profibrinolyti...

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