Heparinase

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Names

[ Name ]:
Heparinase

[Synonym ]:
1H-Indole-3-propanamide, N-[9-[(6-chloro-1,2,3,4-tetrahydro-9-acridinyl)amino]nonyl]-
N-{9-[(6-Chloro-1,2,3,4-tetrahydro-9-acridinyl)amino]nonyl}-3-(1H-indol-3-yl)propanamide

Chemical & Physical Properties

[ Density]:
1.2±0.1 g/cm3

[ Boiling Point ]:
795.4±60.0 °C at 760 mmHg

[ Molecular Formula ]:
C₃₃H₄₁ClN₄O

[ Molecular Weight ]:
545.158

[ Flash Point ]:
434.8±32.9 °C

[ Exact Mass ]:
544.296875

[ LogP ]:
8.37

[ Vapour Pressure ]:
0.0±2.8 mmHg at 25°C

[ Index of Refraction ]:
1.643

[ Storage condition ]:
20°C

Safety Information

[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ RIDADR ]:
NONH for all modes of transport

Articles

Differential expression of plasma microRNA in preeclamptic patients at delivery and 1 year postpartum.

Am. J. Obstet. Gynecol. 213 , 367.e1-9, (2015)

Preeclampsia (PE) is a hypertensive disorder of pregnancy characterized by widespread maternal endothelial dysfunction. Although clinical signs subside following delivery, long-term risks associated w...

Enhanced soluble expression of recombinantFlavobacterium heparinumheparinase I inEscherichia coliby fusing it with various soluble partners

Protein Expr. Purif. 83(2) , 169-76, (2012)

Highlights ► IF2 and SUMO can significantly improve the soluble expression of HepA. ► The fusion proteins can be conveniently purified by a single step of IMAC. ► Fusion proteins of HepA retain their ...

Heparin from bovine intestinal mucosa: glycans with multiple sulfation patterns and anticoagulant effects.

Thromb. Haemost. 107(5) , 903-15, (2012)

Pharmaceutical grade heparins from porcine intestine and bovine lung consist mainly of repeating tri-sulfated units, of the disaccharide →4-α-IdoA2S-1→4-α-GlcNS6S-1→. Heparin preparations from bovine ...

Heparinase
Heparinase II
N-(benzo[d][1,3]dioxol-5-ylmethyl)-2-(4-(3-ethyl-1,2,4-oxadiazol-5-yl)-2-oxoquinolin-1(2H)-yl)acetamide
N-cyclohexyl-2-(4-(3-cyclopropyl-1,2,4-oxadiazol-5-yl)-2-oxoquinolin-1(2H)-yl)acetamide
2-[4-(3-cyclopropyl-1,2,4-oxadiazol-5-yl)-2-oxo-1,2-dihydroquinolin-1-yl]-N-[(4-methylphenyl)methyl]acetamide
2-(4-(3-cyclopropyl-1,2,4-oxadiazol-5-yl)-2-oxoquinolin-1(2H)-yl)-N-(2-methoxybenzyl)acetamide
N-(1,3-benzodioxol-5-ylmethyl)-2-[4-(3-cyclopropyl-1,2,4-oxadiazol-5-yl)-2-oxoquinolin-1(2H)-yl]acetamide
2-(4-(3-cyclopropyl-1,2,4-oxadiazol-5-yl)-2-oxoquinolin-1(2H)-yl)-N-(2-fluorobenzyl)acetamide
N-[(3-methoxyphenyl)methyl]-2-{2-oxo-4-[3-(propan-2-yl)-1,2,4-oxadiazol-5-yl]-1,2-dihydroquinolin-1-yl}acetamide
2-[5-(4-fluorophenyl)-7-methyl-3-oxo-2H,3H-[1,2,4]triazolo[4,3-c]pyrimidin-2-yl]-N-(2-methoxyphenyl)acetamide
N-(3-chloro-2-fluorophenyl)-2-(5-(4-fluorophenyl)-7-methyl-3-oxo-[1,2,4]triazolo[4,3-c]pyrimidin-2(3H)-yl)acetamide
N-(4-(dimethylamino)phenyl)-2-(5-methyl-4-oxo-7-phenyl-4,5-dihydro-3H-pyrrolo[3,2-d]pyrimidin-3-yl)acetamide

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