NU1025

Suppliers

Names

[ Name ]:
NU1025

[Synonym ]:
8-Hydroxy-2-methylquinazolin-4(1H)-one
2-methylquinazoline-4,8-diol
MFCD00942555
4,8-quinazolinediol, 2-methyl-
8-hydroxy-2-methyl-1H-quinazolin-4-one
8-hydroxy-2-methylquinazolin-4(3H)-one
8-Hydroxy-2-methyl-4(1H)-quinazolinone
4(1H)-Quinazolinone, 8-hydroxy-2-methyl-
8-Hydroxy-2-methyl-4(3H)-quinazolinone

Chemical & Physical Properties

[ Density]:
1.4±0.1 g/cm3

[ Boiling Point ]:
345.4±44.0 °C at 760 mmHg

[ Melting Point ]:
253-258ºC

[ Molecular Formula ]:
C₉H₈N₂O₂

[ Molecular Weight ]:
176.172

[ Flash Point ]:
162.7±28.4 °C

[ Exact Mass ]:
176.058578

[ PSA ]:
65.98000

[ LogP ]:
0.35

[ Appearance of Characters ]:
solid | off-white

[ Vapour Pressure ]:
0.0±0.8 mmHg at 25°C

[ Index of Refraction ]:
1.678

[ Storage condition ]:
−20°C

[ Water Solubility ]:
DMSO: 35 mg/mL, soluble

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H302-H319

[ Precautionary Statements ]:
P305 + P351 + P338

[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves

[ Hazard Codes ]:
Xn: Harmful;

[ Risk Phrases ]:
22

[ Safety Phrases ]:
26

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

[ HS Code ]:
2933990090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

8-METHOXY-2-METHYL-3H-QUINAZOLIN-4-ONE
3-METHOXY-2-AMINOBENZAMIDE
2-N-Acetylamino-3-methoxybenzamide
8-Methoxyquinazolin-4-ol
8-methoxy-2-methyl-4H-benzo[d][1,3]oxazin-4-one
8-hydroxy-4(3H)-quinazoline

DownStream

Customs

[ HS Code ]: 2933990090

[ Summary ]:
2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Articles

Rapamycin-resistant poly (ADP-ribose) polymerase-1 overexpression is a potential therapeutic target in lymphangioleiomyomatosis.

Am. J. Respir. Cell. Mol. Biol. 51(6) , 738-49, (2014)

Lymphangioleiomyomatosis (LAM) is a female-predominant cystic lung disease that can lead to respiratory failure. LAM cells typically have inactivating tuberous sclerosis complex 2 (TSC2) mutations and...

3-{[4-(5-chloro-2-methylphenyl)piperazin-1-yl]carbonyl}-6-methyl[1,2,3]triazolo[1,5-a]pyrazin-4(5H)-one
N1-(2-hydroxy-2-(4-(methylthio)phenyl)ethyl)-N2-(3-(2-oxopiperidin-1-yl)phenyl)oxalamide
6-methyl-4-oxo-N-[2-(2-thienyl)ethyl]-4,5-dihydro[1,2,3]triazolo[1,5-a]pyrazine-3-carboxamide
1-Ethyl-3-(2-hydroxy-2-(4-(methylthio)phenyl)ethyl)urea
N-(2,3-dihydro-1H-inden-1-yl)-6-methyl-4-oxo-4,5-dihydro[1,2,3]triazolo[1,5-a]pyrazine-3-carboxamide
N-(2,5-difluorobenzyl)-6-methyl-4-oxo-4,5-dihydro[1,2,3]triazolo[1,5-a]pyrazine-3-carboxamide
6-phenyl-2-(4-phenylpiperazine-1-carbonyl)pyrazolo[1,5-a]pyrazin-4(5H)-one
N-benzyl-2-(4-((1-phenyl-1H-1,2,3-triazol-5-yl)methyl)piperazin-1-yl)acetamide
(2-bromophenyl)(4-((1-phenyl-1H-1,2,3-triazol-5-yl)methyl)piperazin-1-yl)methanone
1-(4-ethylbenzoyl)-4-[(1-phenyl-1H-1,2,3-triazol-5-yl)methyl]piperazine

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