Chondroitinase AC

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Names

[ CAS No. ]:
9047-57-8

[ Name ]:
Chondroitinase AC

[Synonym ]:
MFCD00130796
Chondroitinase AC

Chemical & Physical Properties

[ Appearance of Characters ]:
lyophilized powder

[ Storage condition ]:
−20°C

[ Water Solubility ]:
0.02 M phosphate buffer: soluble (pH 7.0)

Safety Information

[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ Safety Phrases ]:
22-24/25

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

Articles

Crystallization and preliminary analysis of chondroitinase AC from Flavobacterium heparinum.

Acta Crystallogr. D Biol. Crystallogr. 54(Pt 2) , 279-280, (1998)

Chondroitinase AC (E.C. 4.2.2.5) overexpressed in its host, Flavobacterium heparinum, was crystallized by vapor diffusion using polyethylene glycol methyl ether as precipitant. It crystallizes in the ...

Anti-tumor activities of chondroitinase AC and chondroitinase B: inhibition of angiogenesis, proliferation and invasion.

Eur. J. Pharmacol. 416 , 213-221, (2001)

In the current study, two specific glycosaminoglycan lyases, chondroitinase AC and chondroitinase B, were utilized to examine the roles of chondroitin sulfates and dermatan sulfate in tumor metastasis...

An improved methodology to produce Flavobacterium heparinum chondroitinases, important instruments for diagnosis of diseases.

Biotechnol. Appl. Biochem. 37(2) , 115-127, (2003)

Chondroitinases are very important tools for the identification and structural analysis of proteoglycans. Enzymic analysis with Flavobacterium heparinum chondroitinases has shown that chondroitin sulp...

chondroitinase abc
Chondroitinase B, from Flavobacterium heparinum
N-Ac-D-Val-NHMe
2-[3-(diaminomethylideneamino)-4-(3,4-dihydroxy-4,5-dimethyloxolan-2-yl)oxy-2,5,6-trihydroxycyclohexyl]guanidine
L-Ac-Phe(NH2)-Gly-OCH2Ph
N-Ac-phenylglycine-OMe