Diprotin A
Suppliers
Names
[ CAS No. ]:
90614-48-5
[ Name ]:
Diprotin A
[Synonym ]:
MFCD00038707
H-ILE-PRO-ILE-OH
ILE-PRO-ILE H2O
Ile-Pro-Ile-OH
H-ILE-PRO-ILE-OH H2O
DIPEPTIDYLPEPTIDASE IV INHIBITOR I
L-Isoleucyl-L-prolyl-L-isoleucine
ILE-PRO-ILE
L-Ile-L-Pro-L-Ile-OH
Chemical & Physical Properties
[ Density]:
1.14 g/cm3
[ Boiling Point ]:
583.1ºC at 760 mmHg
[ Molecular Formula ]:
C17H31N3O4
[ Molecular Weight ]:
341.44600
[ Flash Point ]:
306.5ºC
[ Exact Mass ]:
341.23100
[ PSA ]:
112.73000
[ LogP ]:
1.99540
[ Index of Refraction ]:
1.517
[ Storage condition ]:
−20°C
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- NR4737000
- CHEMICAL NAME :
- L-Isoleucine, N-(1-L-isoleucyl-L-prolyl)-
- CAS REGISTRY NUMBER :
- 90614-48-5
- LAST UPDATED :
- 199212
- DATA ITEMS CITED :
- 1
- MOLECULAR FORMULA :
- C17-H31-N3-O4
- MOLECULAR WEIGHT :
- 341.51
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD - Lethal dose
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- >250 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- JANTAJ Journal of Antibiotics. (Japan Antibiotics Research Assoc., 2-20-8 Kamiosaki, Shinagawa-ku, Tokyo, 141, Japan) V.2-5, 1948-52; V.21- 1968- Volume(issue)/page/year: 37,422,1984
Safety Information
[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
[ RIDADR ]:
NONH for all modes of transport
[ WGK Germany ]:
3
[ RTECS ]:
NR4737000
Articles
J. Sci. Food Agric. 95(7) , 1514-20, (2015)
Dietary mineral deficiency, hypertension and diabetes have become serious human health problems. Dietary approaches are increasingly being investigated to address these issues. Identification of food-...
PLoS ONE 9(9) , e105829, (2014)
The study is designed to find out the biochemical basis of antidiabetic property of Symplocos cochinchinensis (SC), the main ingredient of 'Nisakathakadi' an Ayurvedic decoction for diabetes. Since di...
Food Funct. 6(1) , 313-20, (2015)
Inhibition of dipeptidyl peptidase-IV (DPP-IV) is used as a means to regulate post-prandial serum glucose in type 2 diabetics. The effect of drug (Sitagliptin®)/peptide and binary peptide mixtures on ...