Pyroglutamate aminopeptidase I

[ Density]:
1.1±0.1 g/cm3

[ Boiling Point ]:
449.2±38.0 °C at 760 mmHg

[ Molecular Formula ]:
C₁₈H₂₀O₃

[ Molecular Weight ]:
284.350

[ Flash Point ]:
161.1±20.3 °C

[ Exact Mass ]:
284.141235

[ LogP ]:
5.69

[ Vapour Pressure ]:
0.0±1.2 mmHg at 25°C

[ Index of Refraction ]:
1.558

[ Symbol ]:

GHS07, GHS08

[ Signal Word ]:
Danger

[ Hazard Statements ]:
H315-H319-H334-H335

[ Precautionary Statements ]:
P261-P305 + P351 + P338-P342 + P311

[ RIDADR ]:
NONH for all modes of transport

Chronic ethanol intake modifies pyrrolidon carboxypeptidase activity in mouse frontal cortex synaptosomes under resting and K+ -stimulated conditions: role of calcium.

Neurosci. Lett. 439(1) , 75-8, (2008)

Pyrrolidon carboxypeptidase (Pcp) is an omega peptidase that removes pyroglutamyl N-terminal residues of peptides such as thyrotrophin-releasing hormone (TRH), which is one of the neuropeptides that h...

Occurrence of the free and Peptide forms of pyroglutamic acid in plasma from the portal blood of rats that had ingested a wheat gluten hydrolysate containing pyroglutamyl peptides.

J. Agric. Food Chem. 54(19) , 6984-8, (2006)

In order to determine pyroglutamic acid levels in plasma, we developed a method based on precolumn derivatization of the carboxyl group of pyroglutamic acid with 2-nitrophenylhydrazine. Eight-week-old...

Differentiation of Leishmania major is impaired by over-expression of pyroglutamyl peptidase I.

Mol. Biochem. Parasitol. 150(2) , 318-29, (2006)

Pyroglutamyl peptidases I (PPI) are cysteine peptidases of the clan CF, family C15, which hydrolyse N-terminal l-pyroglutamyl residues (l-pGlu). The l-pGlu modification is a post-transcriptional modif...

More Articles