2-Methylnaphthalene
Suppliers
Names
[ CAS No. ]:
91-57-6
[ Name ]:
2-Methylnaphthalene
[Synonym ]:
2-METHYL NAPHTHALENE
beta-Methylnaphthalene
2-methyl-1-naphtoic acid
2-Methylnaphthalen-1-carbonsaeure
2-methyl-naphthalene
B-METHYLNAPHTHALENE
EINECS 202-078-3
L66J B1
2-methyl-1-naphthoic acid
2-metylnaphtalene
2-METHYLNAPHTHALENE FOR SYNTHESIS
2-Methylnaphthalen
2-Methylnaphthalene
2-methyl-1-naphthalenecarboxylic acid
2-methylnaphtalene
2-methylnaphthoic acid
MFCD00004118
2-METHYLNAPTHALENE
β-Methylnaphthalene
Naphthalene, 2-methyl-
SS-METHYLNAPHTHALENE
Fasudil Impurity 13
Chemical & Physical Properties
[ Density]:
1.0±0.1 g/cm3
[ Boiling Point ]:
239.9±3.0 °C at 760 mmHg
[ Melting Point ]:
34-36 °C(lit.)
[ Molecular Formula ]:
C11H10
[ Molecular Weight ]:
142.197
[ Flash Point ]:
97.8±0.0 °C
[ Exact Mass ]:
142.078247
[ LogP ]:
3.91
[ Vapour Pressure ]:
0.1±0.2 mmHg at 25°C
[ Index of Refraction ]:
1.617
[ Stability ]:
Stable. Incompatible with strong oxidizing agents.
[ Water Solubility ]:
0.00246 g/100 mL
[ Freezing Point ]:
34.5℃
MSDS
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- QJ9635000
- CHEMICAL NAME :
- Naphthalene, 2-methyl-
- CAS REGISTRY NUMBER :
- 91-57-6
- LAST UPDATED :
- 199801
- DATA ITEMS CITED :
- 11
- MOLECULAR FORMULA :
- C11-H10
- MOLECULAR WEIGHT :
- 142.21
- WISWESSER LINE NOTATION :
- L66J C1
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 1630 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- LDLo - Lowest published lethal dose
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 1 gm/kg
- TOXIC EFFECTS :
- Lungs, Thorax, or Respiration - structural or functional change in trachea or bronchi Lungs, Thorax, or Respiration - other changes
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 28500 mg/kg/81W-C
- TOXIC EFFECTS :
- Tumorigenic - equivocal tumorigenic agent by RTECS criteria Lungs, Thorax, or Respiration - tumors
MUTATION DATA
- TYPE OF TEST :
- Sister chromatid exchange
- TEST SYSTEM :
- Human Lymphocyte
- DOSE/DURATION :
- 250 umol/L
- REFERENCE :
- MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 208,155,1988 *** OCCUPATIONAL EXPOSURE LIMITS *** OEL-RUSSIA:STEL 20 mg/m3 JAN 1993 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - M1659 No. of Facilities: 633 (estimated) No. of Industries: 10 No. of Occupations: 15 No. of Employees: 3498 (estimated) NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - M1659 No. of Facilities: 376 (estimated) No. of Industries: 5 No. of Occupations: 5 No. of Employees: 4359 (estimated) No. of Female Employees: 1608 (estimated)
Safety Information
[ Symbol ]:
GHS02, GHS06, GHS08
[ Signal Word ]:
Danger
[ Hazard Statements ]:
H225-H301 + H311 + H331-H370
[ Precautionary Statements ]:
P210-P260-P280-P301 + P310-P311
[ Personal Protective Equipment ]:
Eyeshields;Faceshields;full-face respirator (US);Gloves;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter
[ Hazard Codes ]:
Xn:Harmful;N:Dangerousfortheenvironment;
[ Risk Phrases ]:
R22;R51/53
[ Safety Phrases ]:
S26-S37/39-S61-S36/37-S24/25-S23-S53
[ RIDADR ]:
UN 3077 9/PG 3
[ WGK Germany ]:
2
[ RTECS ]:
QJ9635000
[ Packaging Group ]:
III
[ Hazard Class ]:
9
[ HS Code ]:
29029080
Synthetic Route
Precursor & DownStream
Precursor
DownStream
Customs
[ HS Code ]: 29029080
Articles
Eur. J. Med. Chem. 43 , 714-40, (2008)
Simplified molecular input line entry system (SMILES) has been utilized in constructing quantitative structure-property relationships (QSPR) for octanol/water partition coefficient of vitamins and org...
J. Med. Chem. 48 , 440-9, (2005)
The purpose of this study was to develop screening and in silico modeling methods to obtain accurate information on the active center of CYP2A6, a nicotine oxidizing enzyme. The inhibitory potencies o...
Eur. J. Med. Chem. 44 , 1941-51, (2009)
A series of naphthalene and non-naphthalene derivatives ( n = 42) having cytochrome P450 2A6 and 2A5 inhibitory activities, reported by Rahnasto et al., were subjected to QSAR and QAAR studies. The an...