Tripelennamine
Suppliers
Names
[ CAS No. ]:
91-81-6
[ Name ]:
Tripelennamine
[Synonym ]:
Piribenzil
Tonaril
N-benzyl-N',N'-dimethyl-N-pyridin-2-yl-ethane-1,2-diamine
Benzoxale
Tripelennamin
Pyribenzamine
Cizaron
N-benzyl-N',N'-dimethyl-N-[2]pyridyl-ethylenediamine
Resistamine
tripelenamin
Tripelennamina
tripelennamine
Pyrinamine base
Chemical & Physical Properties
[ Density]:
1.0683 (rough estimate)
[ Boiling Point ]:
185 - 190ºC at 1.7 mm Hg
[ Melting Point ]:
25°C
[ Molecular Formula ]:
C16H21N3
[ Molecular Weight ]:
255.35800
[ Exact Mass ]:
255.17400
[ PSA ]:
19.37000
[ LogP ]:
2.64980
[ Index of Refraction ]:
nD25 1.5759-1.5765
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- US2800000
- CHEMICAL NAME :
- Pyridine, 2-(benzyl(2-(dimethylamino)ethyl)amino)-
- CAS REGISTRY NUMBER :
- 91-81-6
- BEILSTEIN REFERENCE NO. :
- 0227074
- LAST UPDATED :
- 199612
- DATA ITEMS CITED :
- 9
- MOLECULAR FORMULA :
- C16-H21-N3
- MOLECULAR WEIGHT :
- 255.40
- WISWESSER LINE NOTATION :
- T6NJ BN1R&2N1&1
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LDLo - Lowest published lethal dose
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 37 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 152 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 43 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 23 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - guinea pig
- DOSE/DURATION :
- 64 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Subcutaneous
- SPECIES OBSERVED :
- Mammal - species unspecified
- DOSE/DURATION :
- 61 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
MUTATION DATA
- TYPE OF TEST :
- Unscheduled DNA synthesis
- TEST SYSTEM :
- Human Liver
- DOSE/DURATION :
- 10 umol/L
- REFERENCE :
- MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 173,229,1986 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - 74620 No. of Facilities: 26 (estimated) No. of Industries: 1 No. of Occupations: 1 No. of Employees: 1324 (estimated) No. of Female Employees: 667 (estimated)