Felodipine 3,5-Dimethyl Ester

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Names

[ CAS No. ]:
91189-59-2

[ Name ]:
Felodipine 3,5-Dimethyl Ester

[Synonym ]:
3,5-Pyridinedicarboxylic acid, 4-(2,3-dichlorophenyl)-1,4-dihydro-2,6-dimethyl-, dimethyl ester
Felodipine 3,5-Dimethyl Ester
Dimethyl 4-(2,3-dichlorophenyl)-2,6-dimethyl-1,4-dihydro-3,5-pyridinedicarboxylate
Felodipine Impurity B
Cleviprex Impurity D
Clevidipine Impurity 3

Chemical & Physical Properties

[ Density]:
1.3±0.1 g/cm3

[ Boiling Point ]:
459.7±45.0 °C at 760 mmHg

[ Molecular Formula ]:
C17H17Cl2NO4

[ Molecular Weight ]:
370.227

[ Flash Point ]:
231.8±28.7 °C

[ Exact Mass ]:
369.053467

[ PSA ]:
64.63000

[ LogP ]:
4.30

[ Vapour Pressure ]:
0.0±1.1 mmHg at 25°C

[ Index of Refraction ]:
1.554

Synthetic Route

Precursor & DownStream

Precursor

  • Methyl acetoacetate
  • 2,3-Dichlorobenzaldehyde
  • (R)-3-ethyl 5-((R)-1-hydroxy-3-(phenylthio)propan-2-yl) 4-(2,3-dichlorophenyl)-2,6-dimethyl-1,4-dihydropyridine-3,5-dicarboxylate
  • Sodium Methylate

DownStream


Related Compounds

  • Proline, 3,5-dimethyl-, methyl ester, (2-alpha-,3-ba-,5-ba-)- (9CI)
  • Essigsaeure-(3,5-dimethyl-2-oxo-5H-furan-5-yl)ester
  • ethyl 3,5-dimethyl-1-phenylpyrazole-4-carboxylate
  • 2-(3,5-DIMETHYL-PHENYL)-THIAZOLE-4-CARBOXYLIC ACID ETHYL ESTER
  • 1-(3,5-dimethyl-4-nitrobenzoyl)azetidine-2R-carboxylic acid methyl ester
  • 5-(3,5-DIMETHYL-PYRAZOL-1-YLMETHYL)-FURAN-2-CARBOXYLIC ACID METHYL ESTER
  • 4-((Cyclohexylamino)methyl)benzoic acid hydrochloride
  • 1-[(2,4-Dichlorophenyl)methyl]-N-(1,1-dimethylethyl)-2-methyl-1H-indole-3-methanamine
  • 2-Methoxy-6-(pyrazol-1-yl)-benzonitrile
  • 1H-3-Benzazepin-7-ol, 8-chloro-2,3,4,5-tetrahydro-5-(3-iodophenyl)-3-methyl-, (S)-
  • 1,3-dioxo-2,3-dihydro-1H-isoindol-2-yl 3-{[(furan-2-yl)methyl]sulfamoyl}benzoate
  • N-(2,2-difluoroethyl)-5-(1H-indol-4-yl)pyrimidin-2-amine
  • (4-Methyl-tetrahydro-furan-2-yl)-methanol
  • N-(1-cyanocyclopentyl)-2-[4-(4-fluorobenzenesulfonyl)-1,4-diazepan-1-yl]acetamide
  • 4,5,6,7-Tetrahydrobenzo[d]isoxazole-3-carbaldehyde
  • 2-{[(3-Methylfuran-2-yl)methyl]sulfanyl}pentan-3-amine