Spantide I TFA

Suppliers

Names

[ Name ]:
Spantide I TFA

[Synonym ]:
M.W. 1497.80 C75H108N20O13
SPANTIDE
1-Arg-7,9-Trp-11-Leu-substance p
SPANTIDE HYDROCHLORIDE
Spantide I
Substance P-[D-Arg1,D-Trp7,9,Leu11]

Chemical & Physical Properties

[ Molecular Formula ]:
C₇₅H₁₀₈N₂₀O₁₃

[ Molecular Weight ]:
1497.79000

[ Exact Mass ]:
1496.84000

[ PSA ]:
548.21000

[ LogP ]:
7.06100

[ Storage condition ]:
-20°C

Safety Information

Articles

Involvement of midbrain tectum neurokinin-mediated mechanisms in fear and anxiety.

Braz. J. Med. Biol. Res. 45(4) , 349-56, (2012)

Electrical stimulation of midbrain tectum structures, particularly the dorsal periaqueductal gray (dPAG) and inferior colliculus (IC), produces defensive responses, such as freezing and escape behavio...

Solution conformation of Substance P antagonists-[D-Arg1, D-Trp7,9, Leu11]-SP, [D-Arg1, D-Pro2, D-Trp7,9, Leu11]-SP and [D-Pro2, D-Trp7,9]-SP by CD, NMR and MD simulations.

Peptides 26 , 875-885, (2005)

Substance P (SP) is an important neuropeptide involved in pain transmission and induction of inflammation. Its antagonists are being extensively investigated for their non-narcotic analgesic and anti-...

Substance P stimulates late-stage rat osteoblastic bone formation through neurokinin-1 receptors.

Neuropeptides 41(1) , 25-31, (2007)

Substance P (SP) is a widely distributed neuropeptide that works as a neurotransmitter and neuromodulator. Recently, SP receptors, particularly neurokinin-1 receptors (NK(1)-Rs) that have a high affin...