6-(3-chloropropoxy)-N- (3-chloro-4-fluorophenyl)-7-Methoxyquinazolin-4-aMine

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Names

[ CAS No. ]:
912556-91-3

[ Name ]:
6-(3-chloropropoxy)-N- (3-chloro-4-fluorophenyl)-7-Methoxyquinazolin-4-aMine

[Synonym ]:
N-(3-Chloro-4-fluorophenyl)-6-(3-chloropropoxy)-7-methoxy-4-quinazolinamine
N-(3-chloro-4-fluorophenyl)-6-(3-chloropropoxy)-7-methoxyquinazolin-4-amine
4-Quinazolinamine, N-(3-chloro-4-fluorophenyl)-6-(3-chloropropoxy)-7-methoxy-

Chemical & Physical Properties

[ Density]:
1.4±0.1 g/cm3

[ Boiling Point ]:
523.3±50.0 °C at 760 mmHg

[ Molecular Formula ]:
C18H16Cl2FN3O2

[ Molecular Weight ]:
396.243

[ Flash Point ]:
270.3±30.1 °C

[ Exact Mass ]:
395.060364

[ PSA ]:
56.27000

[ LogP ]:
5.22

[ Vapour Pressure ]:
0.0±1.4 mmHg at 25°C

[ Index of Refraction ]:
1.636

[ Storage condition ]:
2-8°C

Safety Information

[ Hazard Codes ]:
Xi

[ HS Code ]:
2933990090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • 1-Bromo-3-chloropropane
  • FAAH-IN-2
  • 6-(3-chloropropoxy)-4-chloro-7-Methoxyquinazoline
  • 3-Chloro-4-fluoroaniline
  • Methyl 2-amino-5-(3-chloropropoxy)-4-methoxybenzoate
  • methyl 5-(3-chloropropoxy)-4-methoxy-2-nitrobenzoate
  • Methyl isovanillate
  • 4(3H)-Quinazolinone, 6-(3-chloropropoxy)-7-Methoxy-
  • 3,4-Dihydro-7-methoxy-4-oxoquinazolin-6-yl acetate

DownStream

  • Gefitinib

Customs

[ HS Code ]: 2933990090

[ Summary ]:
2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%