Piroxantrone

Suppliers

Names

[ CAS No. ]:
91441-23-5

[ Name ]:
Piroxantrone

[Synonym ]:
5-<(2'-Methylaminophenyl)-thio>-4-brom-2-phenyl-3-pyridazinon
4-bromo-5-(2-methylamino-phenylsulfanyl)-2-phenyl-2H-pyridazin-3-one
5-[(3-aminopropyl)amino]-7,10-dihydroxy-2-{2-[(2-hydroxyethyl)amino]ethyl}anthra(1,9-cd)pyrazol-6(2H)-one
3(2H)-Pyridazinone,4-bromo-5-[[2-(methylamino)phenyl]thio]-2-phenyl
Piroxantrone

Chemical & Physical Properties

[ Density]:
1.435g/cm3

[ Boiling Point ]:
785ºC at 760mmHg

[ Molecular Formula ]:
C21H25N5O4

[ Molecular Weight ]:
411.45400

[ Flash Point ]:
428.6ºC

[ Exact Mass ]:
411.19100

[ PSA ]:
145.66000

[ LogP ]:
2.05870

[ Index of Refraction ]:
1.738

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
CB4586000
CHEMICAL NAME :
Anthra(1,9-cd)pyrazol-6(2H)-one, 5-((3-aminopropyl)amino)-7,10-dihydroxy-2-(2-((2- hydroxyethyl)amino)ethyl)-
CAS REGISTRY NUMBER :
91441-23-5
LAST UPDATED :
199612
DATA ITEMS CITED :
2
MOLECULAR FORMULA :
C21-H25-N5-O4
MOLECULAR WEIGHT :
411.51

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

MUTATION DATA

TYPE OF TEST :
Mutation test systems - not otherwise specified
TEST SYSTEM :
Rodent - mouse Leukocyte
DOSE/DURATION :
11300 nmol/L
REFERENCE :
BCPCA6 Biochemical Pharmacology. (Pergamon Press Inc., Maxwell House, Fairview Park, Elmsford, NY 10523) V.1- 1958- Volume(issue)/page/year: 34,3499,1985

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • 5-[(3-aminopropyl)amino]-2-[2-[(2-hydroxyethyl)amino]ethyl]-7,10-bis-(phenylmethoxy)anthra[1,9-cd]pyrazol-6(2H)-one
  • 5-[(3-aminopropyl)amino]-2-[2-[(2-hydroxyethyl)(phenylmethyl)amino]ethyl]-7,10-bis(phenylmethoxy)anthra[1,9-cd]pyrazol-6(2H)-one
  • 5-chloro-2-[2-[(2-hydroxyethyl)(phenylmethyl)amino]ethyl]-7,10-bis-(phenylmethoxy)anthra[1,9-cd]pyrazol-6(2H)-one
  • 1,3-Diaminopropane

DownStream

Related Compounds

  • piroxantrone hydrochloride
  • piroxantrone hydrochloride
  • 4-((Cyclohexylamino)methyl)benzoic acid hydrochloride
  • 1-[(2,4-Dichlorophenyl)methyl]-N-(1,1-dimethylethyl)-2-methyl-1H-indole-3-methanamine
  • 2-Methoxy-6-(pyrazol-1-yl)-benzonitrile
  • 1H-3-Benzazepin-7-ol, 8-chloro-2,3,4,5-tetrahydro-5-(3-iodophenyl)-3-methyl-, (S)-
  • (4-Methyl-tetrahydro-furan-2-yl)-methanol
  • N-(1-cyanocyclopentyl)-2-[4-(4-fluorobenzenesulfonyl)-1,4-diazepan-1-yl]acetamide
  • 4,5,6,7-Tetrahydrobenzo[d]isoxazole-3-carbaldehyde
  • N-methyl-N-[1-(5,6,7,8-tetrahydroquinazolin-4-yl)piperidin-3-yl]methanesulfonamide
  • tert-Butyl-DL-alanine
  • 4-amino-N-[2-tert-butyl-1-(tetrahydro-2H-pyran-4-ylmethyl)-1H-benzimidazol-5-yl]-N-ethylbenzenesulfonamide