Bromfenac Sodium

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Names

[ Name ]:
Bromfenac Sodium

[Synonym ]:
Bromfenacsodium
BENZENEACETIC ACID, 2-AMINO-3-(4-BROMOBENZOYL)-, MONOSODIUM SALT
BENZENEACETIC ACID,2-AMINO-3-(4-BROMOBENZOYL)-, SODIUM SALT (1:1)
bromfenac sodium salt
{2-amino-3-[(4-bromophényl)carbonyl]phényl}acétate de sodium
sodium {2-amino-3-[(4-bromophenyl)carbonyl]phenyl}acetate
Sodium [2-amino-3-(4-bromobenzoyl)phenyl]acetate
Natrium-{2-amino-3-[(4-bromphenyl)carbonyl]phenyl}acetat
Bronuck
Benzeneacetic acid, 2-amino-3-(4-bromobenzoyl)-, sodium salt (1:1)
Bromfenac sodium

Chemical & Physical Properties

[ Boiling Point ]:
562.2ºC at 760 mmHg

[ Melting Point ]:
285ºC

[ Molecular Formula ]:
C₁₅H₁₁BrNNaO₃

[ Molecular Weight ]:
356.147

[ Flash Point ]:
293.8ºC

[ Exact Mass ]:
354.981995

[ PSA ]:
83.22000

[ LogP ]:
2.13590

[ Appearance of Characters ]:
faint yellow to dark yellow

[ Vapour Pressure ]:
1.77E-13mmHg at 25°C

[ Storage condition ]:
2-8°C

[ Water Solubility ]:
H2O: ≥5mg/mL

MSDS

Click to get detail MSDS

Safety Information

[ Symbol ]:

GHS09

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H400

[ Precautionary Statements ]:
P273

[ Hazard Codes ]:
N

[ Risk Phrases ]:
50

[ Safety Phrases ]:
61

[ RIDADR ]:
UN 3077 9 / PGIII

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Articles

Multiparametric assay using HepaRG cells for predicting drug-induced liver injury.

Toxicol. Lett. 236 , 16-24, (2015)

The utility of HepaRG cells as an in vitro cell-based assay system for assessing drug-induced liver injury (DILI) risk was investigated. Seventeen DILI-positive and 15 DILI-negative drugs were selecte...

Efficacy of ophthalmic nonsteroidal antiinflammatory drugs in suppressing anterior capsule contraction and secondary posterior capsule opacification.

J. Cataract Refract. Surg. 35(9) , 1614-8, (2009)

To evaluate the efficacy of ophthalmic nonsteroidal and steroidal antiinflammatory drugs in preventing anterior capsule contraction and secondary posterior capsule opacification (PCO) using an experim...

Cyclooxygenase (COX)-inhibiting drug reduces HSV-1 reactivation in the mouse eye model.

Curr. Eye Res. 34(3) , 171-6, (2009)

To examine the effects of COX inhibitors on suppressing HSV-1 reactivation in a mouse model.BALB/c mice were latently infected with HSV-1 and treated by 0.1% bromfenac Na eye drops, 0.1% pranoprofen e...

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