Bromfenac Sodium

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Names

[ Name ]:
Bromfenac Sodium

[Synonym ]:
Bromfenacsodium
BENZENEACETIC ACID, 2-AMINO-3-(4-BROMOBENZOYL)-, MONOSODIUM SALT
BENZENEACETIC ACID,2-AMINO-3-(4-BROMOBENZOYL)-, SODIUM SALT (1:1)
bromfenac sodium salt
{2-amino-3-[(4-bromophényl)carbonyl]phényl}acétate de sodium
sodium {2-amino-3-[(4-bromophenyl)carbonyl]phenyl}acetate
Sodium [2-amino-3-(4-bromobenzoyl)phenyl]acetate
Natrium-{2-amino-3-[(4-bromphenyl)carbonyl]phenyl}acetat
Bronuck
Benzeneacetic acid, 2-amino-3-(4-bromobenzoyl)-, sodium salt (1:1)
Bromfenac sodium

Chemical & Physical Properties

[ Boiling Point ]:
562.2ºC at 760 mmHg

[ Melting Point ]:
285ºC

[ Molecular Formula ]:
C₁₅H₁₁BrNNaO₃

[ Molecular Weight ]:
356.147

[ Flash Point ]:
293.8ºC

[ Exact Mass ]:
354.981995

[ PSA ]:
83.22000

[ LogP ]:
2.13590

[ Appearance of Characters ]:
faint yellow to dark yellow

[ Vapour Pressure ]:
1.77E-13mmHg at 25°C

[ Storage condition ]:
2-8°C

[ Water Solubility ]:
H2O: ≥5mg/mL

MSDS

Click to get detail MSDS

Safety Information

[ Symbol ]:

GHS09

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H400

[ Precautionary Statements ]:
P273

[ Hazard Codes ]:
N

[ Risk Phrases ]:
50

[ Safety Phrases ]:
61

[ RIDADR ]:
UN 3077 9 / PGIII

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Articles

Multiparametric assay using HepaRG cells for predicting drug-induced liver injury.

Toxicol. Lett. 236 , 16-24, (2015)

The utility of HepaRG cells as an in vitro cell-based assay system for assessing drug-induced liver injury (DILI) risk was investigated. Seventeen DILI-positive and 15 DILI-negative drugs were selecte...

Efficacy of ophthalmic nonsteroidal antiinflammatory drugs in suppressing anterior capsule contraction and secondary posterior capsule opacification.

J. Cataract Refract. Surg. 35(9) , 1614-8, (2009)

To evaluate the efficacy of ophthalmic nonsteroidal and steroidal antiinflammatory drugs in preventing anterior capsule contraction and secondary posterior capsule opacification (PCO) using an experim...

Cyclooxygenase (COX)-inhibiting drug reduces HSV-1 reactivation in the mouse eye model.

Curr. Eye Res. 34(3) , 171-6, (2009)

To examine the effects of COX inhibitors on suppressing HSV-1 reactivation in a mouse model.BALB/c mice were latently infected with HSV-1 and treated by 0.1% bromfenac Na eye drops, 0.1% pranoprofen e...

Bromfenac sodium
Bromfenac-d4 sodium
iofensulfuron-sodium
Danshensu Sodium Salt
Tectorigenin sodium sulfonate
PMPA sodium salt
2-{Imidazo[1,2-a]pyridin-3-yl}-2-methylpropanenitrile
(1R,2S,4S)-2-(Trifluoromethyl)bicyclo[2.2.1]heptane-2-carboxylic acid
tert-butyl N-[(6,8-dimethoxy-1,2,3,4-tetrahydroisoquinolin-1-yl)methyl]carbamate
Methyl 5-(methylcarbamoyl)piperidine-2-carboxylate
4-{[4-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)-N-methylbutanamido]methyl}benzoic acid
2-{1-[6-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)pyridin-2-yl]-N-[2-(methylsulfanyl)ethyl]formamido}acetic acid
[1-(4-Chloro-3-methylphenyl)-3-(methylsulfanyl)propan-2-yl]hydrazine
1-[(3R)-3-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)pentanoyl]-4-hydroxypiperidine-4-carboxylic acid
N-(4-fluorophenyl)-4-(2,3,5,6-tetramethylphenyl)-1,3-thiazol-2-amine
1-(5-Bromo-2-tert-butyl-phenyl)hexahydropyrimidine-2,4-dione

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