5-Fluoro-6-hydroxy-2,3-dihydro-1H-inden-1-one

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Names

[ CAS No. ]:
917885-01-9

[ Name ]:
5-Fluoro-6-hydroxy-2,3-dihydro-1H-inden-1-one

[Synonym ]:
5-fluoro-6-hydroxyindan-1-one

Chemical & Physical Properties

[ Density]:
1.412g/cm3

[ Boiling Point ]:
323.17ºC at 760 mmHg

[ Molecular Formula ]:
C9H7FO2

[ Molecular Weight ]:
166.14900

[ Flash Point ]:
149.248ºC

[ Exact Mass ]:
166.04300

[ PSA ]:
37.30000

[ LogP ]:
1.66020

[ Index of Refraction ]:
1.603

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • 3-(3-fluoro-4-hydroxyphenyl)propionic acid
  • 5-FLUORO-6-METHOXY-2,3-DIHYDRO-1H-INDEN-1-ONE
  • 3-Fluoro-4-methoxybenzaldehyde
  • 3-(3-Fluoro-4-methoxyphenyl)propanoic acid

DownStream

  • 6-fluoro-7-hydroxy-3,4-dihydro-2H-isoquinolin-1-one
  • reversed lactam

Related Compounds

  • 5-Fluoro-2-{[1-(2-phenylethyl)piperidin-4-yl]oxy}pyrimidine
  • 2-[1-[(3-Methylphenyl)methyl]piperidin-4-yl]oxy-4-(trifluoromethyl)pyrimidine
  • 6-Cyclopropyl-N-[(4-methylphenyl)methyl]pyrimidine-4-carboxamide
  • 5-Ethyl-4-methyl-6-(4-{2-methylpyrido[3,4-d]pyrimidin-4-yl}piperazin-1-yl)pyrimidine
  • N-[1-(2,5-Dimethylphenyl)sulfonylpiperidin-4-yl]-N,6-dimethylpyrimidin-4-amine
  • 3-{4-[(2-Methyl-1,3-oxazol-4-yl)methyl]piperazin-1-yl}-6-(4-methylphenyl)pyridazine
  • 2-(4-{[4-(Trifluoromethyl)pyrimidin-2-yl]oxy}piperidin-1-yl)quinoxaline
  • N,6-dimethyl-N-{1-[2-(trifluoromethoxy)benzenesulfonyl]piperidin-4-yl}pyrimidin-4-amine
  • 2-[4-(6-Cyclopropylpyridazin-3-yl)piperazin-1-yl]-1,3-benzothiazole
  • 4-Cyclopropyl-6-{4-[6-(furan-2-yl)pyridazin-3-yl]piperazin-1-yl}pyrimidine
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