Ro 15-4513

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Names

[ CAS No. ]:
91917-65-6

[ Name ]:
Ro 15-4513

[Synonym ]:
Ethyl-8-azido-5,6-dihydro-5-methyl-6-oxo-4H-imidazo-1,4-benzodiazepine-3-carboxylate
Tocriscreen Total

Chemical & Physical Properties

[ Molecular Formula ]:
C15H14N6O3

[ Molecular Weight ]:
326.31000

[ Exact Mass ]:
326.11300

[ PSA ]:
114.18000

[ LogP ]:
1.96706

MSDS

Click to get detail MSDS

Safety Information

[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ RIDADR ]:
NONH for all modes of transport

Articles

Rats with different thresholds for DMCM-induced clonic convulsions differ in the sleep-time of diazepam and [(3)H]-Ro 15-4513 binding.

Epilepsy Res. 98(2-3) , 216-22, (2012)

The current study investigated the possible inherent relationship between convulsions and sleep involving the GABA(A)/benzodiazepine site complex. The aim of this study was to determine if rats with h...

Antagonism of the ethanol-like discriminative stimulus effects of ethanol, pentobarbital, and midazolam in cynomolgus monkeys reveals involvement of specific GABA(A) receptor subtypes.

J. Pharmacol. Exp. Ther. 331(1) , 142-52, (2009)

The gamma-aminobutyric acid (GABA)(A) receptors mediating the discriminative stimulus effects of ethanol were studied by comparing the potency of ethyl-8-azido-5,6-dihydro-5-methyl-6-oxo-4H-imidazol(1...

Modulation of diazepam-insensitive GABA(A) receptors by micromolar concentrations of thyroxine and related compounds in vitro.

Brain Res. 1490 , 1-8, (2013)

The effects of thyroxine and its related compounds on the benzodiazepine-insensitive γ-aminobutyric acid type A (GABA(A)) receptors were studied. Thyroxine at micromolar concentrations potentiated the...


More Articles

Related Compounds

  • Ro-15-2041
  • Ro 15-8670
  • (2S,5R,6E)-3,3-dimethyl-7-oxo-6-(2-oxopropylidene)-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid
  • Cefetamet
  • Temarotene
  • sodium,(6R,7R)-7-[[(2E)-2-(2-amino-1,3-thiazol-4-yl)-2-methoxyiminoacetyl]amino]-3-methyl-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate
  • 1-(1,1-Difluoro-3-hydroxypropyl)naphthalen-2-ol
  • 1-(2-Amino-3,3,3-trifluoropropyl)naphthalen-2-ol
  • 2-(Bromomethyl)-4,4,4-trifluoro-3-(trifluoromethyl)but-1-ene
  • 3-(1,1,1,3,3,3-Hexafluoropropan-2-yl)-1,2-oxazol-5-amine
  • 4,4,4-Trifluoro-3-(trifluoromethyl)butanethioamide
  • 3,3,3-Trifluoro-2-(trifluoromethyl)propanethioamide
  • 1-[4,4,4-Trifluoro-2-methyl-3-(trifluoromethyl)butan-2-yl]cyclopropan-1-amine
  • 3-Amino-3-(1,1,1,3,3,3-hexafluoropropan-2-yl)cyclobutan-1-ol
  • [3,3-Difluoro-1-(1,1,1,3,3,3-hexafluoropropan-2-yl)cyclobutyl]methanamine
  • 5-(1,1,1,3,3,3-hexafluoropropan-2-yl)-1-methyl-1H-pyrazole-4-carboxylic acid
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