Zatebradine hydrochloride

[ Density]:
1.115g/cm3

[ Boiling Point ]:
612.5ºC at 760mmHg

[ Molecular Formula ]:
C₂₆H₃₇ClN₂O₅

[ Molecular Weight ]:
493.03500

[ Flash Point ]:
324.3ºC

[ Exact Mass ]:
492.23900

[ PSA ]:
60.47000

[ LogP ]:
3.95270

Click to get detail MSDS

[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ Safety Phrases ]:
22-24/25

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

Abnormal diastolic currents in ventricular myocytes from spontaneous hypertensive heart failure rats.

Am. J. Physiol. Heart Circ. Physiol. 291(5) , H2192-8, (2006)

Hypertension is a common cause of heart failure, and ventricular arrhythmias are a major cause of death in heart failure. The spontaneous hypertension heart failure (SHHF) rat model was used to study ...

Effects of tachycardia on regional wall motion in acute ischemic canine heart.

Tohoku J. Exp. Med. 203(2) , 111-21, (2004)

Tachycardia accompanies the preload reduction. Our aim is to assess the effect of the heart rate change on wall motion in ischemic heart. In 8 dogs with occlusion of left anterior descending artery, w...

Validation of a high-sensitivity assay for zatebradine in dried blood spots of human blood at pg/ml concentrations using HILIC-MS/MS.

Bioanalysis 2(11) , 1863-71, (2010)

One of the main reasons for the increased popularity of dried blood spots (DBS) is related to the 3Rs principles (replacement, refinement and reduction) for animal use in drug development. The small b...

More Articles