phenyltoloxamine

Suppliers

Names

[ CAS No. ]:
92-12-6

[ Name ]:
phenyltoloxamine

[Synonym ]:
Feniltolossamina [DCIT]
Phenyltoloxamine
Phenoxadrine
Antin
[2-(2-benzyl-phenoxy)-ethyl]-dimethyl-amine
Histionex
2-Dimethylamino-1-(2-benzyl-phenoxy)-aethan
Bistrimin
Phenoxadrin
UNII-K65LB6598J
Phenyl-toloxamin
Phentoloxamine
Bristamin
[2-(2-Benzyl-phenoxy)-aethyl]-dimethyl-amin

Chemical & Physical Properties

[ Density]:
1.022g/cm3

[ Boiling Point ]:
359.2ºC at 760 mmHg

[ Molecular Formula ]:
C17H21NO

[ Molecular Weight ]:
255.35500

[ Flash Point ]:
106ºC

[ Exact Mass ]:
255.16200

[ PSA ]:
12.47000

[ LogP ]:
3.21780

[ Index of Refraction ]:
1.552

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
KH2376000
CHEMICAL NAME :
Ethanamine, N,N-dimethyl-2-(2-(phenylmethyl)phenoxy)-
CAS REGISTRY NUMBER :
92-12-6
BEILSTEIN REFERENCE NO. :
1986598
LAST UPDATED :
199701
DATA ITEMS CITED :
6
MOLECULAR FORMULA :
C17-H21-N-O
MOLECULAR WEIGHT :
255.39

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
1400 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
PSCBAY Psychopharmacology Service Center, Bulletin. (Bethesda, MD) V.1-3, 1961-65. For publisher information, see PSYBB9. Volume(issue)/page/year: 2,17,1963
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
1127 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
PSCBAY Psychopharmacology Service Center, Bulletin. (Bethesda, MD) V.1-3, 1961-65. For publisher information, see PSYBB9. Volume(issue)/page/year: 2,17,1963
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
246 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
PSCBAY Psychopharmacology Service Center, Bulletin. (Bethesda, MD) V.1-3, 1961-65. For publisher information, see PSYBB9. Volume(issue)/page/year: 2,17,1963
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intravenous
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
55 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
PSCBAY Psychopharmacology Service Center, Bulletin. (Bethesda, MD) V.1-3, 1961-65. For publisher information, see PSYBB9. Volume(issue)/page/year: 2,17,1963 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - 83250 No. of Facilities: 19 (estimated) No. of Industries: 1 No. of Occupations: 9 No. of Employees: 934 (estimated) No. of Female Employees: 506 (estimated)

Synthetic Route

Precursor & DownStream

Precursor

  • 2-Benzylphenol
  • 2-benzylphenol-2-bromoethylether
  • Dimethylamine
  • sodium o-benzylphenolate
  • 2-Chloroethyldimethylamine

DownStream

  • 2-(2-benzylphenoxy)ethyl-trimethylazanium,iodide

Related Compounds

  • Phenyltoloxamine citrate
  • Phenyltoloxamine bisulfate
  • N-Desmethyl Phenyltoloxamine Hydrochloride
  • 3-Bromo-5-methoxy-4-(prop-2-yn-1-yl)pyridine
  • 3-(5-Chloro-2-hydroxyphenyl)-3-hydroxypropanenitrile
  • (1S)-1-(2-bromo-3-fluorophenyl)ethan-1-ol
  • 2-({3-[({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)methyl]-2,2-difluorocyclopropyl}formamido)-3-methoxy-2-methylpropanoic acid
  • 1-(3-Bromoprop-1-en-2-yl)-4,5-difluoro-2-nitrobenzene
  • 4-(Dodecyloxy)-3-methoxyphenol
  • 1-Butyl-4-(cyclohexylethynyl)benzene
  • 1,4-Bis(2-(naphthalen-2-yl)phenyl)buta-1,3-diyne
  • 5-(3-Methoxyphenylthio)pentan-2-ol
  • 2-Bromo-4-(4-chloro-2-fluorophenyl)pyrimidine
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