phenyltoloxamine

Suppliers

Names

[ CAS No. ]:
92-12-6

[ Name ]:
phenyltoloxamine

[Synonym ]:
Feniltolossamina [DCIT]
Phenyltoloxamine
Phenoxadrine
Antin
[2-(2-benzyl-phenoxy)-ethyl]-dimethyl-amine
Histionex
2-Dimethylamino-1-(2-benzyl-phenoxy)-aethan
Bistrimin
Phenoxadrin
UNII-K65LB6598J
Phenyl-toloxamin
Phentoloxamine
Bristamin
[2-(2-Benzyl-phenoxy)-aethyl]-dimethyl-amin

Chemical & Physical Properties

[ Density]:
1.022g/cm3

[ Boiling Point ]:
359.2ºC at 760 mmHg

[ Molecular Formula ]:
C17H21NO

[ Molecular Weight ]:
255.35500

[ Flash Point ]:
106ºC

[ Exact Mass ]:
255.16200

[ PSA ]:
12.47000

[ LogP ]:
3.21780

[ Index of Refraction ]:
1.552

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
KH2376000
CHEMICAL NAME :
Ethanamine, N,N-dimethyl-2-(2-(phenylmethyl)phenoxy)-
CAS REGISTRY NUMBER :
92-12-6
BEILSTEIN REFERENCE NO. :
1986598
LAST UPDATED :
199701
DATA ITEMS CITED :
6
MOLECULAR FORMULA :
C17-H21-N-O
MOLECULAR WEIGHT :
255.39

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
1400 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
PSCBAY Psychopharmacology Service Center, Bulletin. (Bethesda, MD) V.1-3, 1961-65. For publisher information, see PSYBB9. Volume(issue)/page/year: 2,17,1963
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
1127 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
PSCBAY Psychopharmacology Service Center, Bulletin. (Bethesda, MD) V.1-3, 1961-65. For publisher information, see PSYBB9. Volume(issue)/page/year: 2,17,1963
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
246 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
PSCBAY Psychopharmacology Service Center, Bulletin. (Bethesda, MD) V.1-3, 1961-65. For publisher information, see PSYBB9. Volume(issue)/page/year: 2,17,1963
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intravenous
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
55 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
PSCBAY Psychopharmacology Service Center, Bulletin. (Bethesda, MD) V.1-3, 1961-65. For publisher information, see PSYBB9. Volume(issue)/page/year: 2,17,1963 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - 83250 No. of Facilities: 19 (estimated) No. of Industries: 1 No. of Occupations: 9 No. of Employees: 934 (estimated) No. of Female Employees: 506 (estimated)

Synthetic Route

Precursor & DownStream

Precursor

  • 2-Benzylphenol
  • 2-benzylphenol-2-bromoethylether
  • Dimethylamine
  • sodium o-benzylphenolate
  • 2-Chloroethyldimethylamine

DownStream

  • 2-(2-benzylphenoxy)ethyl-trimethylazanium,iodide

Related Compounds

  • Phenyltoloxamine citrate
  • Phenyltoloxamine bisulfate
  • N-Desmethyl Phenyltoloxamine Hydrochloride
  • Methyl 2-bromo-6-cyano-3-formylphenylacetate
  • Methyl 2-bromo-6-cyano-4-(trifluoromethyl)phenylacetate
  • 5-Bromo-6-chloro-2-phenylpyrimidin-4(3H)-one
  • 1-Oxa-8-azaspiro[4.6]undecane hydrochloride
  • 1-But-3-ynyl-3,3,4-trimethylpiperidine
  • 4-But-3-ynyl-2-ethyl-2-methylmorpholine
  • 4-Amino-N-cyclohexyl-1-propyl-1H-pyrazole-3-carboxamide
  • (2S)-1-(3-tert-butylphenyl)propan-2-amine
  • (2R)-1-(2-fluoro-4-methylphenyl)propan-2-amine
  • 2-Methoxy-4-(((2-methoxyphenyl)imino)methyl)phenol hydrochloride