Phenazine

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Names

[ CAS No. ]:
92-82-0

[ Name ]:
Phenazine

[Synonym ]:
acridizine
Phenazine
MFCD00005023
dibenzopyrazine
dibenzo-p-diazine
EINECS 202-193-9
dibenzo{b,e}pyrazine
Dibenzoparadiazine
azophenylene
9,10-diazaanthracene

Chemical & Physical Properties

[ Density]:
1.3±0.1 g/cm3

[ Boiling Point ]:
357.2±15.0 °C at 760 mmHg

[ Melting Point ]:
172-176 °C(lit.)

[ Molecular Formula ]:
C12H8N2

[ Molecular Weight ]:
180.205

[ Flash Point ]:
160.3±11.7 °C

[ Exact Mass ]:
180.068741

[ PSA ]:
25.78000

[ LogP ]:
2.84

[ Vapour Pressure ]:
0.0±0.8 mmHg at 25°C

[ Index of Refraction ]:
1.740

[ Water Solubility ]:
insoluble

MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
SG1360000
CHEMICAL NAME :
Phenazine
CAS REGISTRY NUMBER :
92-82-0
BEILSTEIN REFERENCE NO. :
0126500
LAST UPDATED :
199712
DATA ITEMS CITED :
8
MOLECULAR FORMULA :
C12-H8-N2
MOLECULAR WEIGHT :
180.22
WISWESSER LINE NOTATION :
T C666 BN INJ

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD - Lethal dose
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
>500 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
400 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intravenous
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
180 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Implant
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
7 mg/kg
TOXIC EFFECTS :
Tumorigenic - equivocal tumorigenic agent by RTECS criteria Kidney, Ureter, Bladder - tumors

MUTATION DATA

TEST SYSTEM :
Insect - Drosophila melanogaster
DOSE/DURATION :
9700 nmol/vial
REFERENCE :
MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 369,75,1996

Safety Information

[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ Hazard Codes ]:
Xn:Harmful;

[ Risk Phrases ]:
R22;R68

[ Safety Phrases ]:
S22-S24/25-S36/37

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

[ RTECS ]:
SG1360000

[ HS Code ]:
29163900

Synthetic Route

Precursor & DownStream

Precursor

  • nitrobenzene
  • 2-Iodoaniline
  • 2-Bromoaniline
  • 2-iodo-4,6-dimethylaniline
  • Phenazine, 5,10-dioxide
  • 1,3-Diphenylurea
  • o-Phenylenediamine
  • 1,2-Dibromobenzene
  • N1-Phenylbenzene-1,2-diamine

DownStream

  • 1-(10H-phenazin-5-yl)ethanone
  • Phenazine,5,10-diacetyl-5,10-dihydro- (6CI,8CI,9CI)
  • Phenazine, 5,10-dioxide
  • Phenazine, 5-oxide
  • 1-Nitrophenazine
  • 5,10-dihydrophenazine-1,4-dione
  • Hemipyocyanine
  • 2-nitrophenazine
  • 5-methyl-10-phenylphenazine
  • 5-Ethylphenazin-5-ium ethyl sulfate

Customs

[ HS Code ]: 2933990090

[ Summary ]:
2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

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Related Compounds

  • phenazine-5
  • fluophenazine
  • phenazine-2-ol
  • benzophenazine
  • N-Oxyphenazine
  • aminophenazine
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  • 2-Methoxy-6-(pyrazol-1-yl)-benzonitrile
  • 1-Chloro-4-fluorophthalazine
  • 1H-3-Benzazepin-7-ol, 8-chloro-2,3,4,5-tetrahydro-5-(3-iodophenyl)-3-methyl-, (S)-
  • (4-Methyl-tetrahydro-furan-2-yl)-methanol
  • N-(1-cyanocyclopentyl)-2-[4-(4-fluorobenzenesulfonyl)-1,4-diazepan-1-yl]acetamide
  • 4,5,6,7-Tetrahydrobenzo[d]isoxazole-3-carbaldehyde
  • tert-Butyl-DL-alanine
  • 2-[3-(3-ethoxypropyl)-4-oxo-benzothiopheno[3,2-d]pyrimidin-2-yl]sulfanyl-N-(4-ethylphenyl)acetamide