Diphtheria toxin CRM197

[ Appearance of Characters ]:
lyophilized powder

[ Storage condition ]:
2-8°C

[ Symbol ]:

GHS06

[ Signal Word ]:
Danger

[ Hazard Statements ]:
H300

[ Precautionary Statements ]:
Missing Phrase - N15.00950417

[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ Hazard Codes ]:
T+

[ Risk Phrases ]:
28

[ Safety Phrases ]:
22-24/25-45-36/37-28

[ RIDADR ]:
3172

[ WGK Germany ]:
3

[ RTECS ]:
XW5807200

[ Packaging Group ]:
I

[ Hazard Class ]:
6.1(a)

Carbohydrate-based vaccines with a glycolipid adjuvant for breast cancer.

Proc. Natl. Acad. Sci. U. S. A. 110(7) , 2517-22, (2013)

Globo H (GH) is a hexasaccharide specifically overexpressed on a variety of cancer cells and therefore, a good candidate for cancer vaccine development. To identify the optimal carrier and adjuvant co...

Glycoconjugate vaccines and immune interactions, and implications for vaccination schedules.

Expert Rev. Vaccines 10(11) , 1621-31, (2011)

Conjugate vaccines using diphtheria toxoid variant (CRM(197)), diphtheria toxoid and tetanus toxoid (TT) as carrier protein may induce immune interactions (interference or impairment as measured by lo...

Antitumor effects of CRM197, a specific inhibitor of HB-EGF, in T-cell acute lymphoblastic leukemia.

Anticancer Res. 31(7) , 2483-8, (2011)

The therapeutic outcome for T-cell acute lymphoblastic leukemia (T-ALL) remains poor; thus, novel, targeted therapies are urgently needed. Recently, we showed that heparin-binding epidermal growth fac...

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